CAS 27223-35-4

4H-[1,3]Oxazino[3,2-d][1,4]benzodiazepine-4,7(6H)-dione, 11-chloro-8,12b-dihydro-2,8-dimethyl-12b-phenyl-

Description:

4H-[1,3]Oxazino[3,2-d][1,4]benzodiazepine-4,7(6H)-dione, 11-chloro-8,12b-dihydro-2,8-dimethyl-12b-phenyl- is a complex organic compound characterized by its unique bicyclic structure that incorporates both oxazine and benzodiazepine moieties. This compound features a chloro substituent and multiple methyl groups, which contribute to its chemical reactivity and potential biological activity. The presence of the benzodiazepine framework suggests possible interactions with neurotransmitter systems, making it of interest in pharmacological research. Its molecular structure includes various functional groups that can influence solubility, stability, and reactivity. The compound is typically synthesized through multi-step organic reactions, and its properties can be studied using techniques such as NMR spectroscopy, mass spectrometry, and X-ray crystallography. Given its complexity, it may exhibit specific pharmacokinetic and pharmacodynamic properties, which could be explored for therapeutic applications. However, detailed studies would be necessary to fully understand its behavior and potential uses in medicinal chemistry.

Formula: C₂₀H₁₇ClN₂O₃

InChI: InChI=1/C20H17ClN2O3/c1-13-10-18(24)23-12-19(25)22(2)17-9-8-15(21)11-16(17)20(23,26-13)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3

InChI key: InChIKey=PWAJCNITSBZRBL-UHFFFAOYSA-N

SMILES: O=C1N2C(C=3C(N(C)C(=O)C2)=CC=C(Cl)C3)(OC(C)=C1)C4=CC=CC=C4

Synonyms:

• (.+-.)-Ketazolam
• 11-Chloro-8,12b-dihydro-2,8-dimethyl-12b-phenyl-4H-[1,3]oxazino[3,2-d][1,4]benzodiazepine-4,7(6H)-dione
• Anseren
• Ansieten
• Anxon
• Contamex
• Loftran
• Nsc 338158
• U 28774
• Unakalm
• 4H-(1,3)Oxazino(3,2-d)(1,4)benzodiazepine-4,7(6H)-dione, 8,12b-dihydro-11-chloro-2,8-dimethyl-12b-phenyl-
• 11-chloro-2,8-dimethyl-12b-phenyl-8,12b-dihydro-4H-[1,3]oxazino[3,2-d][1,4]benzodiazepine-4,7(6H)-dione
• Ketazolam [USAN:INN:BAN]
• 4H-(1,3)Oxazino(3,2-d)(1,4)benzodiazepine-4,7(6H)-dione, 11-chloro-8,12b-dihydro-2,8-dimethyl-12b-phenyl- (8CI)(9CI)
• UNII-92A214MD7Y
• 4H-[1,3]Oxazino[3,2-d][1,4]benzodiazepine-4,7(6H)-dione, 11-chloro-8,12b-dihydro-2,8-dimethyl-12b-phenyl-
• DEA No. 2772
• Ketazolamum [INN-Latin]
• Ketazolamum
• 4H-(1,3)-Oxazino(3,2-d)(1,4)benzodiazepine-4,7(6H)-dione, 11-chloro-8,12b-dihydro-2,8-dimethyl-
• ketazolam USP/EP/BP
• Ketazolam (1.0mg/ml in Acetonitrile)

Ketazolam

Controlled Product

CAS: 27223-35-4

Stability Unstable in Solution
Applications A psychotropic benzodiazepine derivative with hypnotic and anxiolytic properties. Controlled Substance.
References Sethy, V.H. et al.: Naun.-Schmeid. Atch. Pharmacol., 301, 157 (1978); Moore, S. et al.: Curr. Therap. Res., 29, 704 (1981); Gutierrez, S.F. et al.: Cien. Pharmac., 5, 37 (1995);

Formula: C₂₀H₁₇ClN₂O₃

Color and Shape: Off White Crystalline

Molecular weight: 368.81

Ref: TR-K165650

Ketazolam (1.0mg/ml in Acetonitrile)

Controlled Product

CAS: 27223-35-4

Formula: C₂₀H₁₇ClN₂O₃

Color and Shape: Single Solution

Molecular weight: 368.81

Ref: TR-KIT5455