CAS 2726463-68-7

2,4-Pyrimidinediamine, 5-bromo-N4-[2-(dimethylphosphinyl)phenyl]-N2-[3,4,5,6-tetrahydro-8-methoxy-3-methyl-6-(1-methylethyl)pyrazolo[3,4-d][1]benzazepin-9-yl]-

Description:

2,4-Pyrimidinediamine, 5-bromo-N4-[2-(dimethylphosphinyl)phenyl]-N2-[3,4,5,6-tetrahydro-8-methoxy-3-methyl-6-(1-methylethyl)pyrazolo[3,4-d][1]benzazepin-9-yl]- is a complex organic compound characterized by its multi-functional groups, including a pyrimidine ring and a phosphinyl moiety. This compound likely exhibits properties typical of pyrimidine derivatives, such as potential biological activity, including antimicrobial or antitumor effects, due to the presence of the pyrimidine structure. The bromine substituent may enhance its reactivity and influence its pharmacological profile. The presence of a dimethylphosphinyl group suggests potential applications in medicinal chemistry, particularly in the development of targeted therapies. Additionally, the intricate structure, which includes a tetrahydro-pyrazolo-benzazepine moiety, indicates that it may interact with various biological targets, making it a candidate for further research in drug discovery. Overall, this compound's unique structural features and functional groups contribute to its potential utility in various chemical and pharmaceutical applications.

Formula: C₂₈H₃₃BrN₇O₂P

Synonyms:

• EGFR-IN-30
• 2,4-Pyrimidinediamine, 5-bromo-N4-[2-(dimethylphosphinyl)phenyl]-N2-[3,4,5,6-tetrahydro-8-methoxy-3-methyl-6-(1-methylethyl)pyrazolo[3,4-d][1]benzazepin-9-yl]-

EGFR-IN-30

CAS: 2726463-68-7

EGFR-IN-30 is an EGFR inhibitor (IC50: 1-10 nM, <1 nM WT/mutants) with potential in cancer research.

Formula: C₂₈H₃₃BrN₇O₂P

Color and Shape: Solid

Molecular weight: 610.49

Ref: TM-T73108