CAS 2730151-31-0

5-Pyrimidinecarbonitrile, 2,4-diamino-6-[(2S,5S)-2-[5-chloro-3,4-dihydro-4-oxo-3-(3-pyridinyl)-2-quinazolinyl]-5-methyl-1-pyrrolidinyl]-

Description:

5-Pyrimidinecarbonitrile, 2,4-diamino-6-[(2S,5S)-2-[5-chloro-3,4-dihydro-4-oxo-3-(3-pyridinyl)-2-quinazolinyl]-5-methyl-1-pyrrolidinyl]- is a complex organic compound characterized by its multi-functional structure, which includes a pyrimidine ring, a cyano group, and various amino and heterocyclic components. This compound is notable for its potential biological activity, particularly in medicinal chemistry, where it may serve as a lead compound in the development of pharmaceuticals targeting specific biological pathways. The presence of the chloro and pyridinyl groups suggests possible interactions with biological receptors or enzymes, enhancing its pharmacological profile. Additionally, the stereochemistry indicated by the (2S,5S) configuration may influence its biological activity and interaction with target sites. As with many such compounds, its solubility, stability, and reactivity will depend on the specific functional groups and their arrangement, making it a subject of interest for further research in drug development and synthetic chemistry.

Formula: C₂₃H₂₀ClN₉O

Synonyms:

• PI3Kδ/γ-IN-3
• 5-Pyrimidinecarbonitrile, 2,4-diamino-6-[(2S,5S)-2-[5-chloro-3,4-dihydro-4-oxo-3-(3-pyridinyl)-2-quinazolinyl]-5-methyl-1-pyrrolidinyl]-

PI3Kδ/γ-IN-3

CAS: 2730151-31-0

PI3Kδ/γ-IN-3 (Compound 58) is an orally active dual inhibitor of PI3Kδ (IC50: 1 nM) and PI3Kγ (IC50: 16 nM).

Formula: C₂₃H₂₀ClN₉O

Color and Shape: Solid

Molecular weight: 473.92

Ref: TM-T63078