CAS 2731228-51-4

Trimetazidine n-Oxide Dihydrochloride

Description:

Trimetazidine n-Oxide Dihydrochloride is a chemical compound that serves as a metabolite of trimetazidine, a drug primarily used for the treatment of angina pectoris and other ischemic heart conditions. This substance is characterized by its dihydrochloride salt form, which enhances its solubility in aqueous solutions, making it suitable for pharmaceutical applications. The compound exhibits properties typical of a zwitterionic structure, which may contribute to its biological activity. Trimetazidine n-Oxide Dihydrochloride is known for its role in improving cellular energy metabolism and protecting cardiac cells from ischemic damage. It functions by modulating fatty acid oxidation and promoting glucose utilization, thereby optimizing energy production in heart tissues. The compound is typically administered in a controlled dosage to ensure efficacy while minimizing potential side effects. As with many pharmaceutical substances, its safety profile and pharmacokinetics are subjects of ongoing research, particularly regarding its long-term effects and interactions with other medications.

Formula: C₁₄H₂₃ClN₂O₄

Synonyms:

• 1-(2,3,4-trimethoxybenzyl)piperazine 1-oxide dihyrochloride
• Trimetazidine Impurity 11 Dihydrochloride (Trimetazidine n-Oxide Dihydrochloride)
• Trimetazidine n-Oxide Dihydrochloride

Trimetazidine N-Oxide DiHCl

CAS: 2731228-51-4

Formula: C₁₄H₂₂N₂O₄·2HCl

Color and Shape: White To Off-White Solid

Molecular weight: 282.34 2*36.46

Ref: 4Z-T-3513

Trimetazidine N-Oxide Dihydrochloride

Controlled Product

CAS: 2731228-51-4

Formula: C₁₄H₂₂N₂O₄ClH

Color and Shape: Neat

Molecular weight: 355.26

Ref: 86-MM0539.13

Trimetazidine n-Oxide Dihydrochloride

Controlled Product

CAS: 2731228-51-4

Applications Trimetazidine n-Oxide Dihydrochloride is a derivative compound of Trimetazidine Dihydrochloride (T795610), a coronary vasodilator. Antianginal.
References Fujita, et al.: Jpn. J. Pharmacol., 17, 19 (1967), Harpey, C., et al.: Cardiovasc. Drug Rev., 6, 292 (1989),

Formula: C₁₄H₂₂N₂O₄·2ClH

Color and Shape: White

Molecular weight: 355.26

Ref: TR-T787605