CAS 27321-96-6

PEG-cholesterol

Description:

PEG-cholesterol, with the CAS number 27321-96-6, is a conjugate of polyethylene glycol (PEG) and cholesterol, commonly used in biochemistry and pharmaceutical applications. This compound typically features a hydrophilic PEG moiety linked to the hydrophobic cholesterol, which enhances its solubility in aqueous environments while maintaining the biological activity of cholesterol. The presence of PEG increases the molecular weight and alters the pharmacokinetics of cholesterol, often leading to improved stability and reduced immunogenicity in drug formulations. PEG-cholesterol is utilized in various applications, including drug delivery systems, liposomal formulations, and as a component in the synthesis of lipid-based nanoparticles. Its amphiphilic nature allows it to form micelles or liposomes, facilitating the encapsulation of hydrophobic drugs. Additionally, PEG-cholesterol can enhance cellular uptake and improve the bioavailability of therapeutic agents, making it a valuable tool in the development of targeted drug delivery systems. Overall, PEG-cholesterol serves as an important compound in the fields of nanomedicine and biopharmaceuticals.

Formula: (C₂H₄O)nC₂₇H₄₆O

Synonyms:

• Poly(oxy-1,2-ethanediyl), α-(3β)-cholest-5-en-3-yl-ω-hydroxy-
• Cholesterol, monoether with polyethylene glycol
• Glycols, polyethylene, monocholesteryl ether
• Cholestane, poly(oxy-1,2-ethanediyl) deriv.
• Polyethylene glycol cholesteryl ether

Chol-PEG

CAS: 27321-96-6

Chol-PEG, a nonionic surfactant (vesicles), serves as a blood-persistent drug delivery system [1] [2].

Formula: C₂₉H₅₀O₂

Color and Shape: Solid

Molecular weight: 430.38108

Ref: TM-T74306