CAS 2734416-95-4

Flunarizine Dihydrochloride Impurity C as Dihydrochloride

Description:

Flunarizine Dihydrochloride Impurity C, with the CAS number 2734416-95-4, is a chemical compound related to flunarizine, a calcium channel blocker primarily used in the treatment of migraine and certain movement disorders. As an impurity, it may arise during the synthesis of flunarizine and can affect the purity and efficacy of the final pharmaceutical product. The dihydrochloride form indicates that the compound is a salt, which typically enhances its solubility in water, making it more bioavailable. In terms of characteristics, impurities like this can vary in their physical properties, such as melting point, solubility, and stability, depending on their molecular structure. The presence of impurities is critical in pharmaceutical formulations, as they can influence the drug's safety, effectiveness, and regulatory compliance. Therefore, understanding the characteristics of such impurities is essential for quality control in drug manufacturing and ensuring patient safety.

Formula: C₂₆H₂₇ClF₂N₂

Synonyms:

• Flunarizine Dihydrochloride Impurity C as Dihydrochloride
• Flunarizine Impurity 7(Dihydrochloride)
• Flunarizine Dihydrochloride EP Impurity C as Dihydrochloride

Flunarizine EP Impurity C (as Dihydrochloride)

Controlled Product

CAS: 2734416-95-4

Formula: C₂₆H₂₆F₂N₂ClH

Color and Shape: Neat

Molecular weight: 477.42

Ref: 86-MM0175.03

4-Defluoro 2-Fluoro Flunarizine Dihydrochloride

Controlled Product

CAS: 2734416-95-4

Stability Hygroscopic
Applications 4-Defluoro 2-Fluoro Flunarizine Dihydrochloride is an impurity of Flunarizine(F455200, Dihydrochloride), which is a calcium channel blocker. Flunarizine is a fluorinated derivative of Cinnarizine and a vasodilator (cerebral and peripheral).
References Desmedt, L.K., et al.: Arzneim.-Forsch., 25, 1408 (1975), Godfraind, T., et al.: Eur. J. Pharmacol., 53, 273 (1979), Nihard, P., et al.: Angiology, 33, 37 (1982), Holmes, B., et al.: Drugs, 27, 6 (1984)

Formula: C₂₆H₂₆F₂N₂HCl

Color and Shape: White Solid

Molecular weight: 404.4923646

Ref: TR-D228705

Flunarizine EP Impurity C

CAS: 2734416-95-4

Formula: C₂₆H₂₆F₂N₂(HCl)

Molecular weight: 404.51 : 2(36.46)

Ref: ST-EA-CP-F140009