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CAS 27415-26-5

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8-Isoprostaglandin F2α

Description:
8-Isoprostaglandin F2α, also known as 8-iso-PGF2α, is a bioactive lipid compound that belongs to the prostaglandin family. It is a product of lipid peroxidation and is considered a marker of oxidative stress in biological systems. This compound is characterized by its potent vasoconstrictive properties and its role in various physiological and pathological processes, including inflammation and cardiovascular function. 8-Isoprostaglandin F2α is known to interact with specific receptors, influencing cellular signaling pathways and contributing to the regulation of blood pressure and platelet aggregation. Its presence in biological fluids can be indicative of oxidative damage and has been studied in the context of various diseases, including cardiovascular disorders and cancer. The compound is typically analyzed using advanced techniques such as mass spectrometry and chromatography due to its complex structure and low concentrations in biological samples. Overall, 8-Isoprostaglandin F2α serves as an important biomarker in research related to oxidative stress and its implications in health and disease.
Formula:C20H34O5
InChI:InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16-,17+,18-,19+/m0/s1
InChI key:InChIKey=PXGPLTODNUVGFL-NAPLMKITSA-N
SMILES:C(/C=C\CCCC(O)=O)[C@H]1[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)C[C@@H]1O
Synonyms:
  • (5Z,8β,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic acid
  • 15(S)-8-Iso-PGF<sub>2α</sub>
  • 15-F<sub>2t</sub>-IsoP
  • 15-F<sub>2t</sub>-Isoprostane
  • 5-Heptenoic acid, 7-[3,5-dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl]-
  • 8-Iso-PGF<sub>2α</sub>
  • 8-Isoprostaglandin F<sub>2α</sub>
  • 8-Isoprostane
  • 8-epi-PGF<sub>2α</sub>
  • 8-epi-Prostaglandin F<sub>2α</sub>
  • See more synonyms
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