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CAS 2746-81-8

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Fluphenazine enanthate

Description:
Fluphenazine enanthate is an antipsychotic medication primarily used in the treatment of schizophrenia and other psychotic disorders. It is a long-acting ester of fluphenazine, a phenothiazine derivative, which allows for extended therapeutic effects with less frequent dosing compared to its parent compound. The substance is typically administered via intramuscular injection, providing a sustained release of the active drug into the bloodstream. Fluphenazine enanthate exhibits a high affinity for dopamine D2 receptors, which is believed to contribute to its antipsychotic properties. Common side effects may include sedation, extrapyramidal symptoms, and potential metabolic changes. As with other antipsychotics, monitoring for adverse effects is essential during treatment. The chemical structure includes a phenothiazine core, and the enanthate moiety enhances its lipophilicity, influencing its pharmacokinetics. Overall, fluphenazine enanthate is an important therapeutic option in managing severe psychiatric conditions, particularly when long-term treatment is necessary.
Formula:C29H38F3N3O2S
InChI:InChI=1S/C29H38F3N3O2S/c1-2-3-4-5-11-28(36)37-21-20-34-18-16-33(17-19-34)14-8-15-35-24-9-6-7-10-26(24)38-27-13-12-23(22-25(27)35)29(30,31)32/h6-7,9-10,12-13,22H,2-5,8,11,14-21H2,1H3
InChI key:InChIKey=LRWSFOSWNAQHHW-UHFFFAOYSA-N
SMILES:C(CCN1CCN(CCOC(CCCCCC)=O)CC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(C(F)(F)F)C3
Synonyms:
  • 1-Piperazineethanol, 4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]-, heptanoate (ester)
  • 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethyl heptanoate
  • 4-[3-(2-Trifluoromethyl-10-phenothiazinyl)propyl]-1-piperazineethanol enanthate
  • Flufenan
  • Fluphenazine Enanthate
  • Heptanoic acid, 2-[4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazinyl]ethyl ester
  • Heptanoic acid, 2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]-1-piperazinyl]ethyl ester
  • Moditen enanthate
  • Prolixin enanthate
  • Sq 16,114
  • Sq 16144
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