CAS 27460-26-0

(24R)-Hydroxycholesterol

Description:

(24R)-Hydroxycholesterol is a sterol and a derivative of cholesterol, characterized by the presence of a hydroxyl group at the 24th carbon position in its steroid structure. This compound plays a significant role in cholesterol metabolism and is involved in various biological processes, including the regulation of cholesterol homeostasis and the modulation of gene expression. It is primarily synthesized in the brain and is known to influence neuronal function and development. As a signaling molecule, (24R)-hydroxycholesterol can cross the blood-brain barrier and is implicated in neuroprotective mechanisms. Its structure contributes to its amphipathic nature, allowing it to interact with cell membranes and proteins. The compound is also studied for its potential implications in neurodegenerative diseases and other health conditions related to cholesterol dysregulation. Due to its biological significance, (24R)-hydroxycholesterol is of interest in both pharmacological research and clinical studies.

Formula: C₂₇H₄₆O₂

InChI: InChI=1S/C27H46O2/c1-17(2)25(29)11-6-18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20+,21+,22-,23+,24+,25-,26+,27-/m1/s1

InChI key: InChIKey=IOWMKBFJCNLRTC-RNCHBCSGSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@H](CC[C@H](C(C)C)O)C)[H])[H]

Synonyms:

• 24-Epicerebrosterol
• Cholest-5-ene-3,24-diol, (3β,24R)-
• Cholest-5-ene-3β,24-diol, (24R)-
• (3β,24R)-Cholest-5-ene-3,24-diol
• (24R)-Hydroxycholesterol
• CHOLEST-5-ENE-3,24(R)-DIOL;24(R)-HYDROXYCHOLESTEROL
• (24R)-24-hydroxycholesterol
• cholest-5-ene-3,24(R)-diol

24(R)-Hydroxycholesterol

CAS: 27460-26-0

Formula: C27H46O2

Purity: >98%

Color and Shape: Solid

Molecular weight: 402.65

Ref: 48-64-0065

24-Epicerebrosterol

Controlled Product

CAS: 27460-26-0

Formula: C₂₇H₄₆O₂

Color and Shape: Neat

Molecular weight: 402.65

Ref: TR-E582280

24(R)-hydroxycholesterol

Controlled Product

CAS: 27460-26-0

24(R)-hydroxycholesterol is a metabolite of cholesterol that can be found in the mitochondria. It has been shown to have acidic and oxygenated properties. 24(R)-hydroxycholesterol is a type of oxysterol, which are compounds that contain an oxygenated hydroxy group. This compound contains a hydroxyl group, which is an oxygen atom attached to hydrogen. The chromatographic analysis of this compound can be done by gas chromatography-mass spectrometry or liquid chromatography-mass spectrometry. 24(R)-hydoxycholesterol is used as a biomarker for adrenocortical carcinoma, but it also has clinical significance as a cholesterol synthesis inhibitor and as an analytical method for mitochondrial cytochromes.

Formula: C₂₇H₄₆O₂

Purity: Min. 95%

Molecular weight: 402.65 g/mol

Ref: 3D-CBA46026