CAS 2747-05-9

4-Methylumbelliferyl acetate

Description:

4-Methylumbelliferyl acetate is a synthetic organic compound commonly used as a fluorogenic substrate in biochemical assays, particularly for the detection of enzymes such as esterases and lipases. It is characterized by its structure, which includes a methylumbelliferyl moiety linked to an acetate group. This compound is typically a white to pale yellow crystalline solid that is soluble in organic solvents like methanol and dimethyl sulfoxide, but less soluble in water. Upon enzymatic hydrolysis, it releases 4-methylumbelliferone, a fluorescent product that emits blue light when excited, making it useful for quantitative analysis in various biological and chemical applications. The compound is stable under normal laboratory conditions but should be stored away from light to prevent degradation. Safety precautions should be taken when handling this substance, as it may pose health risks if ingested or inhaled. Overall, 4-Methylumbelliferyl acetate is a valuable tool in molecular biology and biochemistry for studying enzyme activity.

Formula: C₁₂H₁₀O₄

InChI: InChI=1/C12H12O4/c1-7-5-12(15-8(2)13)16-11-6-9(14)3-4-10(7)11/h3-6,12,14H,1-2H3

InChI key: InChIKey=HXVZGASCDAGAPS-UHFFFAOYSA-N

SMILES: CC=1C=2C(=CC(OC(C)=O)=CC2)OC(=O)C1

Synonyms:

• (4-Methyl-2-oxochromen-7-yl) acetate
• 2-Acetoxymethyl-5-(1,3-Dioxolan-2-Yl)Furan
• 2H-1-Benzopyran-2-one, 7-(acetyloxy)-4-methyl-
• 4-Methyl-7-acetoxycoumarin
• 4-Methylumbeliferyl acetate
• 4-Methylumbelliferone 7-acetate
• 4-Methylumbelliferone acetate
• 4-Methylumbelliferyl acetate
• 4-methyl-2-oxo-2H-chromen-7-yl acetate
• 7-(Acetyloxy)-4-methyl-2H-1-benzopyran-2-one
• 7-(Acetyloxy)-4-methylcoumarin
• 7-Hydroxy-4-methylcoumarin acetate
• 7-hydroxy-4-methyl-2H-chromen-2-yl acetate
• Coumarin, 7-hydroxy-4-methyl-, acetate
• NSC 1059
• NSC 31658
• NSC 44763
• NSC 688806
• Umbelliferone, 4-methyl-, acetate
• β-Methylumbelliferone acetate
• 4-Methylumbelliferyl(Mub)Acetate
• MUACETATE
• ACETIC ACID 4-METHYLUMBELLIFERYL ESTER
• 7-(ACETYLOXY)-4-METHYL-2-BENZOPYRONE
• B-METHYLUMBELLIFERYL ACETATE
• MUB ACETATE
• 4-MU-ACETATE
• MU-AC
• 4-METHYLUMBELLIFERYL ACETATE, FOR FLUORE SCENCE
• BETA-METHYLUMBELLIFERYL ACETATE
• 4-METHYLUMBELLIFERYL ACETATE*CRYSTALLINE
• 7-ACETOXY-4-METHYLCOUMARIN
• METHYLUMBELLIFERYL ACETATE
• METHYLUMBELLIFERYL ACETATE, 4-

7-Acetoxy-4-methylcoumarin

CAS: 2747-05-9

Formula: C₁₂H₁₀O₄

Purity: >98.0%(GC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 218.21

Ref: 3B-A1527

4-Methyl-2-oxo-2H-chromen-7-yl acetate

CAS: 2747-05-9

Formula: C₁₂H₁₀O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 218.2054

Ref: IN-DA003NCI

7-Acetoxy-4-methylcoumarin

CAS: 2747-05-9

7-Acetoxy-4-methylcoumarin

Purity: 99%

Molecular weight: 218.21g/mol

Ref: 54-OR345252

7-Acetoxy-4-methylcoumarin

CAS: 2747-05-9

7-Acetoxy-4-methylcoumarin

Purity: ≥80%

Molecular weight: 218.21g/mol

Ref: 54-BUP17992

7-Acetoxy-4-methoxycoumarin

CAS: 2747-05-9

7-Acetoxy-4-methoxycoumarin

Purity: 98%

Molecular weight: 234.20g/mol

Ref: 54-OR345000

Hymecromone Acetate

CAS: 2747-05-9

Color and Shape: Neat

Ref: 86-MM0294.04

Sodium Cromoglicate Impurity 15

CAS: 2747-05-9

Formula: C₁₂H₁₀O₄

Molecular weight: 218.21

Ref: 4Z-C-225016

4-Methylumbelliferyl acetate

CAS: 2747-05-9

Formula: C₁₂H₁₀O₄

Molecular weight: 218.21

Ref: 7W-GC1749

7-Acetoxy-4-methylcoumarin

CAS: 2747-05-9

7-Acetoxy-4-methylcoumarin is an inhibitor of GST and can inhibit AFB1-DNA binding in vitro.Cost-effective and quality-assured.

Formula: C₁₂H₁₀O₄

Purity: 88.44% - 97.10%

Color and Shape: Beige Crystalline Flakes And Needles

Molecular weight: 218.21

Ref: TM-T7037

4-Methylumbelliferyl acetate

CAS: 2747-05-9

Fluorogenic substrate for carboxylesterase

Formula: C₁₂H₁₀O₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 218.21 g/mol

Ref: 3D-EM16008

7-ACETOXY-4-METHYLCOUMARIN

CAS: 2747-05-9

Formula: C₁₂H₁₀O₄

Purity: 98%

Color and Shape: No data available.

Molecular weight: 218.208

Ref: 10-F300779

4-Methylumbelliferyl acetate - 95%

CAS: 2747-05-9

4-Methylumbelliferyl acetate is a fluorescent compound that can be used to measure the activity of cytochrome P450 enzymes. The fluorescence intensity of 4-methylumbelliferyl acetate increases when it reacts with substrates and inhibitors in vitro. This chemical has been shown to inhibit the enzyme cyclooxygenase in rat liver microsomes, which may lead to blood disorders. It also inhibits coumarin derivatives and human pathogens, such as erythromycin-resistant Staphylococcus aureus (MRSA). 4-Methylumbelliferyl acetate is used as a substrate for polymerase chain reaction (PCR) analysis because it is not susceptible to hydrolysis by esterases.

Formula: C₁₂H₁₀O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 218.21 g/mol

Ref: 3D-EM166026

Hymecromone Acetate

CAS: 2747-05-9

Formula: C₁₂H₁₀O₄

Molecular weight: 218.21

Ref: ST-EA-CP-H32005