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CAS 274901-16-5

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Vildagliptin

Description:
Vildagliptin is an oral antihyperglycemic agent primarily used in the management of type 2 diabetes mellitus. It belongs to the class of drugs known as dipeptidyl peptidase-4 (DPP-4) inhibitors, which function by enhancing the levels of incretin hormones, thereby increasing insulin secretion and decreasing glucagon release in response to meals. This mechanism helps to lower blood glucose levels. Vildagliptin is characterized by its relatively low molecular weight and specific chemical structure, which includes a piperazine ring and a 2-cyano-4-(trifluoromethyl)phenyl moiety. The substance is typically administered in tablet form and is often used in combination with other antidiabetic medications to improve glycemic control. Its pharmacokinetics indicate a moderate half-life, allowing for once-daily dosing. Common side effects may include gastrointestinal disturbances and headache, but it is generally well-tolerated. As with any medication, it is essential for patients to consult healthcare professionals for personalized advice and monitoring while using Vildagliptin.
Formula:C17H25N3O2
InChI:InChI=1S/C17H25N3O2/c18-9-14-2-1-3-20(14)15(21)10-19-16-5-12-4-13(6-16)8-17(22,7-12)11-16/h12-14,19,22H,1-8,10-11H2/t12?,13?,14-,16?,17?/m0/s1
InChI key:InChIKey=SYOKIDBDQMKNDQ-XWTIBIIYSA-N
SMILES:N(CC(=O)N1[C@H](C#N)CCC1)C23CC4(O)CC(C2)CC(C3)C4
Synonyms:
  • (-)-(2S)-1-[[(3-Hydroxytricyclo[3.3.1.1[3,7]]dec-1-yl)amino]acetyl]pyrrolidine-2-carbonitrile
  • (2S)-1-[2-[(3-Hydroxy-1-adamantyl)amino]acetyl]pyrrolidine-2-carbonitrile
  • (2S)-1-[2-[(3-Hydroxytricyclo[3.3.1.1<sup>3,7</sup>]dec-1-yl)amino]acetyl]-2-pyrrolidinecarbonitrile
  • (2S)-1-[N-(3-hydroxytricyclo[3.3.1.1~3,7~]dec-1-yl)glycyl]pyrrolidine-2-carbonitrile
  • (3R)-3-amino-1-[6-(trifluoromethyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one phosphate (1:1)
  • (S)-1-[2-[(3-Hydroxyadamant-1-yl)amino]acetyl]pyrrolidine-2-carbonitrile
  • 2-Pyrrolidinecarbonitrile, 1-[2-[(3-hydroxytricyclo[3.3.1.1<sup>3,7</sup>]dec-1-yl)amino]acetyl]-, (2S)-
  • 2-Pyrrolidinecarbonitrile, 1-[[(3-hydroxytricyclo[3.3.1.1<sup>3,7</sup>]dec-1-yl)amino]acetyl]-, (2S)-
  • Dsp 7238
  • Galvus
  • See more synonyms
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Found 16 products.
  • Vildagliptin

    CAS:
    Vildagliptin (LAF237), an oral DPP-4 inhibitor with hypoglycemic effects, is metabolized and excreted in urine.
    Formula:C17H25N3O2
    Purity:97.81% - >99.99%
    Color and Shape:White Crystalline Powder
    Molecular weight:303.40
  • 2-Pyrrolidinecarbonitrile, 1-[2-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-, (2S)-

    CAS:
    Formula:C17H25N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:303.3993

    Ref: IN-DA002TWS

    1g
    25.00€
    5g
    65.00€
    10g
    90.00€
    1kg
    330.00€
    25g
    113.00€
    50g
    194.00€
    5kg
    To inquire
    100g
    239.00€
    10kg
    To inquire
    10mg
    24.00€
  • Vildagliptin

    CAS:
    Vildagliptin
    Purity:≥95%
    Molecular weight:303.4g/mol

    Ref: 54-BUP14844

    2g
    284.00€
    10mg
    63.00€
    25mg
    80.00€
    50mg
    96.00€
    100mg
    129.00€
    500mg
    178.00€
  • Vildagliptin

    CAS:
    Formula:C17H25N3O2
    Purity:≥ 98.0%
    Color and Shape:White to off-white powder
    Molecular weight:303.40

    Ref: 7W-GP4588

    1g
    292.00€
    100mg
    77.00€
    250mg
    138.00€
  • Vildagliptin

    CAS:
    Vildagliptin
    Purity:98%
    Molecular weight:303.4g/mol

    Ref: 54-OR1029298

    1g
    32.00€
    5g
    51.00€
    25g
    165.00€
    100g
    428.00€
    500g
    1,408.00€
  • Vildagliptin

    CAS:
    Formula:C17H25N3O2
    Color and Shape:White To Off-White Solid
    Molecular weight:303.41

    Ref: 4Z-V-222

    5mg
    To inquire
    10mg
    444.00€
    25mg
    635.00€
    50mg
    825.00€
    100mg
    To inquire
  • Vildagliptin

    CAS:
    Formula:C17H25N3O2
    Purity:>98.0%(T)(HPLC)
    Color and Shape:White to Light yellow powder to crystal
    Molecular weight:303.41

    Ref: 3B-V0203

    1g
    379.00€
    200mg
    111.00€
  • Vildagliptin

    CAS:
    Formula:C17H25N3O2
    Color and Shape:Neat
    Molecular weight:303.40

    Ref: 04-C17916000

    100mg
    151.00€
  • Vildagliptin

    CAS:
    Formula:C17H25N3O2
    Color and Shape:Neat
    Molecular weight:303.40

    Ref: 86-MM3564.00

    250mg
    1,653.00€
  • Vildagliptin Impurity 13

    CAS:
    Formula:C24H33N5O3
    Color and Shape:White To Off-White Solid
    Molecular weight:439.56

    Ref: 4Z-V-2220

    5mg
    To inquire
    10mg
    To inquire
    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • Vildagliptin

    Controlled Product
    CAS:
    <p>Stability Hygroscopic<br>Applications Glyptins are class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. Aside from their use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic.<br>References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),<br></p>
    Formula:C17H25N3O2
    Color and Shape:White
    Molecular weight:303.40

    Ref: TR-V305000

    1g
    511.00€
    10mg
    93.00€
    500mg
    499.00€
  • N-Nitroso-Vildagliptin

    Controlled Product
    CAS:
    Formula:C17H24N4O3
    Color and Shape:Neat
    Molecular weight:332.4

    Ref: TR-N365450

    10mg
    98.00€
    50mg
    401.00€
    100mg
    732.00€
  • Vildagliptin

    CAS:
    <p>Dipeptidyl peptidase 4 inhibitor</p>
    Formula:C17H25N3O2
    Purity:Min. 95%
    Color and Shape:White Powder
    Molecular weight:303.4 g/mol

    Ref: 3D-FV29102

    1g
    804.00€
    2g
    1,213.00€
    100mg
    244.00€
    250mg
    382.00€
    500mg
    594.00€
  • Vildagliptin - Bio-X ™

    CAS:
    <p>Vildagliptin is an antihyperglycemic agent that is used for the management of type 2 diabetes mellitus. This drug is a dipeptidyl peptidase 4 inhibitor and prevents the degradation of glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). This leads to improved glycemic control.</p>
    Formula:C17H25N3O2
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:303.4 g/mol

    Ref: 3D-BV164521

    10mg
    135.00€
  • Dehydroxy Vildagliptin

    Controlled Product
    CAS:
    <p>Applications Dehydroxy Vildagliptin is the impurity of Glyptins(V305000) which are class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. Aside from their use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic.<br>References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),<br></p>
    Formula:C17H25N3O
    Color and Shape:Neat
    Molecular weight:287.4

    Ref: TR-D357360

    500mg
    1,022.00€
  • Vildagliptin-13C5

    Controlled Product
    CAS:
    Formula:C5C12H25N3O2
    Color and Shape:Neat
    Molecular weight:308.363

    Ref: TR-V305004

    25mg
    17,136.00€