As of my last update in October 2023, the chemical substance with the CAS number 2749637-13-4 does not have an assigned index name or widely available information in public databases. This could indicate that it is a novel compound, potentially under research or development, or it may not yet have been characterized extensively in the literature. Typically, substances with unassigned index names may be in the early stages of study, and their properties, such as molecular structure, reactivity, and potential applications, may not be fully documented. For accurate and detailed information, it is advisable to consult specialized chemical databases, scientific literature, or regulatory agencies that may provide insights into its characteristics once they become available. If you are looking for specific properties or applications, further research or inquiry into recent publications may yield more information as it becomes accessible.

Valproic acid-d
4
(sodium salt) is intended for use as an internal standard for the quantification of valproic acid  by GC- or LC-MS. Valproic acid is an analog of the natural fatty acid valeric acid that inhibits class I histone deacetylases (HDACs) with an IC
50
value of approximately 2 mM.
1
It decreases the number of axon branches in sensory neurons isolated from newborn rat dorsal root ganglia, an effect that is reversed by inositol-1,4,5-trisphosphate (1,4,5-IP
3
).
2
In vivo
, valproic acid inhibits amyloid-β deposition and neuritic plaque formation and decreases escape latency in the Morris water maze, indicating improved memory performance, in the APP23 transgenic mouse model of Alzheimer's disease.
3
Valproic acid has anticonvulsant activity in the pentylenetetrazol seizure threshold test in mice (ED
50
= 0.71 mmol/kg) but induces neurotoxicity when administered at doses greater than or equal to 1.2 mmol/kg.
4
Formulations containing valproic acid have been used to treat bipolar disorder and various seizure disorders.

INDEX NAME NOT YET ASSIGNED

2749637-13-4: As of my last update in October 2023, the chemical substance with the CAS number 2749637-13-4 does not have an assigned index name or widely available information in public databases. This could indicate that it is a novel compound, potentially under research or development, or it may not yet have been characterized extensively in the literature. Typically, substances with unassigned index names may be in the early stages of study, and their properties, such as molecular structure, reactivity, and potential applications, may not be fully documented. For accurate and detailed information, it is advisable to consult specialized chemical databases, scientific literature, or regulatory agencies that may provide insights into its characteristics once they become available. If you are looking for specific properties or applications, further research or inquiry into recent publications may yield more information as it becomes accessible.

CAS 2749637-13-4

INDEX NAME NOT YET ASSIGNED

Sodium 2-(Propyl-1,1-d2)pentanoate-3,3-d2

Ref: TR-S674501