CAS 2753-45-9

Mebeverine hydrochloride

Description:

Mebeverine hydrochloride is a synthetic antispasmodic agent primarily used to relieve symptoms of irritable bowel syndrome (IBS) and other gastrointestinal disorders. It functions by relaxing the smooth muscles of the gastrointestinal tract, thereby alleviating spasms and associated discomfort. The compound is characterized by its chemical formula, which includes a methoxy group and a vinyl group, contributing to its pharmacological properties. Mebeverine hydrochloride is typically administered orally and is well-absorbed in the gastrointestinal tract, with a relatively short half-life. It is known for its minimal side effects, making it a preferred choice for patients with IBS. The substance is usually available in various dosage forms, including tablets and capsules. Its safety profile is generally favorable, but like all medications, it should be used under medical supervision, particularly in individuals with pre-existing health conditions or those taking other medications. Overall, mebeverine hydrochloride is an effective therapeutic option for managing gastrointestinal spasms and improving patient quality of life.

Formula: C₂₅H₃₅NO₅·ClH

InChI: InChI=1S/C25H35NO5.ClH/c1-6-26(19(2)17-20-9-12-22(28-3)13-10-20)15-7-8-16-31-25(27)21-11-14-23(29-4)24(18-21)30-5;/h9-14,18-19H,6-8,15-17H2,1-5H3;1H

InChI key: InChIKey=PLGQWYOULXPJRE-UHFFFAOYSA-N

SMILES: C(OCCCCN(C(CC1=CC=C(OC)C=C1)C)CC)(=O)C2=CC(OC)=C(OC)C=C2.Cl

Synonyms:

• 1-Butanol, 4-[ethyl(p-methoxy-α-methylphenethyl)amino]-, veratrate, hydrochloride
• 4-(Ethyl(p-methoxy-alpha-methylphenethyl)amino)butyl veratrate hydrochloride
• 4-[Ethyl(p-methoxy-α-methylphenethyl)amino]butyl veratrate hydrochloride
• 4-{Ethyl[1-(4-Methoxyphenyl)Propan-2-Yl]Amino}Butyl 3,4-Dimethoxybenzoate Hydrochloride (1:1)
• 4′-[N-Ethyl-1′′-methyl-2′′-(4′′′-methoxyphenyl)ethylamino]butyl 3,4-dimethoxybenzoate hydrochloride
• Benzoic acid, 3,4-dimethoxy-, 4-(ethyl(2-(4-methoxyphenyl)-1-methylethyl)amino)butyl ester, hydrochloride
• Benzoic acid, 3,4-dimethoxy-, 4-[ethyl[2-(4-methoxyphenyl)-1-methylethyl]amino]butyl ester, hydrochloride (1:1)
• Colaspa
• Colofac
• Colospasmin
• Colospasmine fort
• Coloverine
• Csag 144
• Duspatal
• Duspatalin
• Duspataline
• Mebaspa
• Mebeverine HCl
• Mebeverine hydrochloride [USAN]
• Nsc 169101
• Rudakol
• Spasmotaline
• Unii-15Vz5Al4Jn
• Veratric acid, 4-(ethyl(p-methoxy-alpha-methylphenethyl)amino)butyl ester, hydrochloride
• Veratric acid, 4-[ethyl(p-methoxy-α-methylphenethyl)amino]-, butyl ester, hydrochloride

MEBEVERINE HYDROCHLORIDE CRS

CAS: 2753-45-9

MEBEVERINE HYDROCHLORIDE CRS

Color and Shape: Added

Ref: 41-Y0002079

Mebeverine hydrochloride

CAS: 2753-45-9

Mebeverine hydrochloride

Formula: C₂₅H₃₅NO₅HCl

Purity: 99.8%

Color and Shape: White

Molecular weight: 465.2282

Ref: 47-1271

Mebeverine impurity standard

CAS: 14367-47-6, 2753-45-9, 93-07-2

Mebeverine impurity standard

Color and Shape: White

Ref: 47-1272

MEBEVERINE FOR SYSTEM SUITABILITY CRS

CAS: 2753-45-9

MEBEVERINE FOR SYSTEM SUITABILITY CRS

Ref: 41-Y0002107

Mebeverine hydrochloride

CAS: 2753-45-9

Mebeverine hydrochloride (Colofac Hydrochloride), a β-phenylethylamine derivative, is a potent α1 repector inhibitor, relaxing the muscles in and around the gut

Formula: C₂₅H₃₅NO₅

Purity: 99.81% - 99.81%

Color and Shape: Solid

Molecular weight: 429.55

Ref: TM-T1053

Mebeverine HCl

CAS: 2753-45-9

Formula: C₂₅H₃₅NO₅·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 429.56 36.46

Ref: 4Z-M-491

Mebeverine hydrochloride

CAS: 2753-45-9

Mebeverine hydrochloride

Purity: ≥98%

Molecular weight: 466.01g/mol

Ref: 54-BUP16992

Mebeverine hydrochloride, Ph. Eur.

CAS: 2753-45-9

Formula: C₂₅H₃₆ClNO₅

Purity: ≤ 0.1%

Color and Shape: White to almost white crystalline powder

Molecular weight: 466.01

Ref: 7W-GP8164

Mebeverine hydrochloride

CAS: 2753-45-9

Formula: C₂₅H₃₆ClNO₅

Molecular weight: 466.01

Ref: 7W-GP9849

Mebeverine hydrochloride

Controlled Product

CAS: 2753-45-9

Formula: C₂₅H₃₅NO₅·ClH

Color and Shape: Neat

Molecular weight: 466.01

Ref: 04-C14798700

Mebeverine Hydrochloride

Controlled Product

CAS: 2753-45-9

Formula: C₂₅H₃₅NO₅·ClH

Color and Shape: Neat

Molecular weight: 466.01

Ref: 86-MM0319.00

Mebeverine Impurity G1

CAS: 2753-45-9

Formula: C₃₇H₅₁NO₈

Color and Shape: White To Off-White Solid

Molecular weight: 637.82

Ref: 4Z-M-4915

Mebeverine Hydrochloride

Controlled Product

CAS: 2753-45-9

Applications Smooth muscle relaxant. Antispasmodic.
References Bertaccini, G., et al.: Farmaco. Ed. Sci., 30, 823 (1975), Robertson, D., et al.: Cardiovasc. Toxicol.,1, 7 (2001), McGovern, S., et al.: J. Med. Chem., 45, 1712 (2002),

Formula: C₂₅H₃₅NO₅·ClH

Color and Shape: White

Molecular weight: 466.01

Ref: TR-M202490

Mebeverine Hydrochloride

Controlled Product

CAS: 2753-45-9

Mebeverine hydrochloride is a drug that is used to treat bowel disease. It inhibits the contractions of the intestinal tract, which can help relieve symptoms of constipation, diarrhea, and bloating. Mebeverine hydrochloride may also be used in combination with other drugs to treat chronic inflammatory bowel disease. The drug interacts with protocatechuic acid and crystalline cellulose in an adsorption isotherm study. This interaction has been shown to have a significant effect on the polymerase chain reaction (PCR) control analysis of bacterial DNA samples. Mebeverine hydrochloride can cause side effects such as nausea, vomiting, headache, dizziness, or dry mouth. These side effects are more likely when taken with methyl ethyl alcohol or mebeverine. These side effects are also more likely in patients who have liver dysfunction or have a history of an allergic reaction to this drug.

Formula: C₂₅H₃₆ClNO₅

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 466.01 g/mol

Ref: 3D-FM25024

Mebeverine hydrochloride

CAS: 2753-45-9

Formula: C₂₅H₃₅NO₅

Color and Shape: Solid

Molecular weight: 429.5491

Ref: IN-DA00BBU2

Mebeverine Hydrochloride

Controlled Product

CAS: 2753-45-9

Color and Shape: Neat

Ref: 61-FOR0319.00