CAS 27548-93-2: Baccatin III

Description:Baccatin III is a naturally occurring chemical compound classified as a diterpene, specifically a taxane, and is primarily derived from the Pacific yew tree (Taxus brevifolia). It is known for its structural complexity, featuring a unique bicyclic core that is characteristic of taxanes. Baccatin III serves as a crucial precursor in the synthesis of the anticancer drug paclitaxel (Taxol), which is used in the treatment of various cancers, including ovarian and breast cancer. The compound exhibits significant biological activity, particularly in its ability to stabilize microtubules and inhibit cell division, making it a valuable subject of research in medicinal chemistry. Baccatin III is typically characterized by its molecular formula, which reflects its composition of carbon, hydrogen, and oxygen atoms. Its solubility properties and stability under various conditions are also of interest in pharmaceutical applications. Overall, Baccatin III plays a vital role in the development of therapeutic agents and continues to be studied for its potential in cancer treatment and other medical applications.

Formula:C₃₁H₃₈O₁₁

InChI:InChI=1S/C31H38O11/c1-15-19(34)13-31(38)26(41-27(37)18-10-8-7-9-11-18)24-29(6,20(35)12-21-30(24,14-39-21)42-17(3)33)25(36)23(40-16(2)32)22(15)28(31,4)5/h7-11,19-21,23-24,26,34-35,38H,12-14H2,1-6H3/t19-,20-,21+,23+,24-,26-,29+,30-,31+/m0/s1

InChI key:InChIKey=OVMSOCFBDVBLFW-VHLOTGQHSA-N

SMILES:O=C(OC1C2C3(OC(=O)C)COC3CC(O)C2(C(=O)C(OC(=O)C)C4=C(C)C(O)CC1(O)C4(C)C)C)C=5C=CC=CC5

Synonyms:
(1Beta,2Alpha,5Beta,7Beta,10Alpha,13Alpha)-4,10-Bis(Acetyloxy)-1,7,13-Trihydroxy-9-Oxo-5,20-Epoxytax-11-En-2-Yl Benzoate
(2Alpha,3Beta,5Beta,7Beta,10Beta,13Alpha)-4,10-Bis(Acetyloxy)-1,7,13-Trihydroxy-9-Oxo-5,20-Epoxytax-11-En-2-Yl Benzoate
(2Alpha,3Xi,5Beta,7Beta,10Beta,13Alpha)-4,10-Bis(Acetyloxy)-1,7,13-Trihydroxy-9-Oxo-5,20-Epoxytax-11-En-2-Yl Benzoatato
(2Alpha,5Beta,7Beta,10Beta,13Alpha)-4,10-Bis(Acetyloxy)-1,7,13-Trihydroxy-9-Oxo-5,20-Epoxytax-11-En-2-Yl Benzoate
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,9,11-trihydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one
7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,9,11-trihydroxy-4a,8,13,13-tetramethyl-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-
7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,9,11-trihydroxy-4a,8,13,13-tetramethyl-, [2aR-(2aα,4β,4aβ,6β,9α,11α,12α,12aα,12bα)]-
Baccatin III
NSC 330753

Found 13 products.

Product data	Purity	Price range	Estimated delivery
7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,9,11-trihydroxy-4a,8,13,13-tetramethyl-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)- REF: IN-DA002U1CCAS: 27548-93-2	- - -	To inquire	Mon 14 Apr 25
Baccatin III REF: TM-T2788CAS: 27548-93-2	98.45%	49.00 €~359.00 €	Mon 14 Apr 25
Baccatin III REF: 54-BUP06406CAS: 27548-93-2	98.45%	213.00 €~536.00 €	Tue 15 Apr 25
Baccatin III REF: 7W-GY1932CAS: 27548-93-2	≥ 98.0%	To inquire	Tue 15 Apr 25
Paclitaxel EP Impurity N (Baccatin III) REF: 4Z-P-2844CAS: 27548-93-2	- - -	To inquire	Tue 15 Apr 25
Baccatin III REF: 10-F600860CAS: 27548-93-2	97%	144.00 €~636.00 €	Thu 17 Apr 25
Paclitaxel EP Impurity N REF: 86-MM1489.04-0025CAS: 27548-93-2	- - -	To inquire	Thu 17 Apr 25
Paclitaxel EP Impurity N REF: 86-MM1489.04CAS: 27548-93-2	- - -	To inquire	Thu 17 Apr 25
Baccatin III REF: BP-BP0225CAS: 27548-93-2	95%~99%	56.00 €~103.00 €	Thu 17 Apr 25
Baccatin iii REF: 5G-89575CAS: 27548-93-2	≥ 95.0 % (HPLC)	200.00 €~13,590.00 €	Wed 23 Apr 25
Baccatin III REF: TR-B101000CAS: 27548-93-2	- - -	291.00 €~392.00 €	Thu 24 Apr 25
Baccatin III REF: 3D-FB18122CAS: 27548-93-2	Min. 97.5 Area-%	181.00 €~1,793.00 €	Fri 25 Apr 25
Baccatin III ((2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12-(Benzoyloxy)-4,9,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2aH)-diyl diacetate) REF: 45-1A07560CAS: 27548-93-2	- - -	- - -	Discontinued product