CAS 2756-87-8
:Monomethyl fumarate
Description:
Monomethyl fumarate (MMF) is an organic compound characterized by its structure as a methyl ester of fumaric acid. It is a colorless to pale yellow liquid with a slightly sweet odor and is soluble in polar solvents such as water and alcohols. MMF is known for its role in the treatment of multiple sclerosis, where it acts as an immunomodulatory agent. The compound exhibits a double bond in its structure, contributing to its reactivity and potential for undergoing various chemical transformations. It has a relatively low molecular weight and is classified as a dicarboxylic acid derivative. In terms of safety, MMF should be handled with care, as it may cause skin and eye irritation upon contact. Its stability is influenced by environmental factors, and it is typically stored in a cool, dry place to maintain its integrity. Overall, monomethyl fumarate is significant in both pharmaceutical applications and chemical research due to its unique properties and biological activity.
Formula:C5H6O4
InChI:InChI=1S/C5H6O4/c1-9-5(8)3-2-4(6)7/h2-3H,1H3,(H,6,7)/b3-2+
InChI key:InChIKey=NKHAVTQWNUWKEO-NSCUHMNNSA-N
SMILES:C(/C=C/C(O)=O)(OC)=O
Synonyms:- (2E)-4-methoxy-4-oxobut-2-enoic acid
- (2Z)-4-methoxy-4-oxobut-2-enoic acid
- (E)-4-Methoxy-4-oxo-but-2-enoic acid
- (E)-4-Methoxy-4-oxobut-2-enoic acid
- 2-Butenedioic acid (2E)-, 1-methyl ester
- 2-Butenedioic acid (2E)-, monomethyl ester
- 2-Butenedioic acid (E)-, monomethyl ester
- Fumaric acid monomethyl ester
- Fumaric acid, methyl ester
- Methyl hydrogen fumarate
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Monomethyl Fumarate
CAS:Formula:C5H6O4Purity:>98.0%(GC)Color and Shape:White to Almost white powder to crystalMolecular weight:130.10Dimethyl Fumarate Related Compound A
CAS:Acyclic polycarboxylic acids and their anhydrides, halides, peroxides and their derivatives, nesoiFormula:C5H6O4Color and Shape:White PowderMolecular weight:130.02661Monomethyl fumarate
CAS:Monomethyl fumarate is a potent agonist of GPR109A .Formula:C5H6O4Purity:99.21%Color and Shape:SolidMolecular weight:130.0987mono-Methyl fumarate
CAS:mono-Methyl fumarateFormula:C5H6O4Purity:98%Color and Shape:SolidMolecular weight:130.09874Dimethyl Fumarate USP Related Compound A (Monomethyl Fumarate)
CAS:Formula:C5H6O4Color and Shape:White To Off-White SolidMolecular weight:130.10mono-Methyl fumarate
CAS:Formula:C5H6O4Purity:≥ 97%Color and Shape:White to off-white powder or solidMolecular weight:130.10Dimethyl Fumarate USP Related Compound A (Monomethyl Fumarate)
CAS:Controlled ProductFormula:C5H6O4Color and Shape:NeatMolecular weight:130.10Monomethyl fumarate
CAS:(E)-4-methoxy-4-oxobut-2-enoic acidFormula:C5H6O4Purity:98%Molecular weight:130.1Fumaric Acid Monomethyl Ester
CAS:Controlled ProductApplications Fumaric Acid Monomethyl Ester is one of the most bioactive anti-psoriatic fumaric acid ester metabolite. Fumaric acid monomethyl ester is potent nicotinic acid receptor agonist. Fumaric acid monomethyl ester has also been shown to selectively stimulate of T helper 2 cytokine response. It is also the active metabolite of Dimethyl Fumarate (D464965), a compound that is used as a treatment for the relapsing forms of multiple sclerosis and psoriasis.
References de Jong, R. et al.: Eur. J. Immunol., 26, 2067 (1996); Litjens, N.H.R. et al.: Br. J. Dermatol., 154, 211 (2006); Schimrigk, S., et al.: Eur. J. Neurol., 13, 604 (2006); Tang, H. et al.: Biochem. Biophys. Res. Comm., 375, 562 (2008)Formula:C5H6O4Color and Shape:NeatMolecular weight:130.1
