CAS 27574-24-9: Tropatepine

Description: Tropatepine, with the CAS number 27574-24-9, is a chemical compound that belongs to the class of tropane alkaloids. It is characterized by its bicyclic structure, which includes a tropane ring, a common feature in many biologically active compounds. Tropatepine exhibits anticholinergic properties, making it relevant in pharmacology, particularly in the treatment of various conditions such as motion sickness and muscle spasms. The compound interacts with muscarinic acetylcholine receptors, leading to effects such as reduced secretions and muscle relaxation. Its chemical properties include solubility in organic solvents and limited solubility in water, which is typical for many alkaloids. Additionally, tropatepine may undergo various chemical reactions, including esterification and alkylation, due to the presence of functional groups in its structure. As with many alkaloids, safety and toxicity profiles should be considered in its handling and application, emphasizing the importance of proper dosage and administration in therapeutic contexts.

Formula: C₂₂H₂₃NS

InChI: InChI=1S/C22H23NS/c1-23-17-10-11-18(23)13-16(12-17)22-19-7-3-2-6-15(19)14-24-21-9-5-4-8-20(21)22/h2-9,17-18H,10-14H2,1H3

InChI key: InChIKey=JOQKFRLFXDPXHX-UHFFFAOYSA-N

SMILES: S1C=2C=CC=CC2C(C=3C=CC=CC3C1)=C4CC5N(C)C(C4)CC5

Synonyms:

• (1S,5S)-3-(dibenzo[b,e]thiepin-11(6H)-ylidene)-8-methyl-8-azabicyclo[3.2.1]octane
• 1-alpha-H,5-alpha-H-Tropane, 3-dibenzo(b,e)thiepin-11(6H)-ylidene-
• 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropane, 3-dibenzo[b,e]thiepin-11(6H)-ylidene-
• 3-(6,11-Dihydrodibenzo(b,e)thiepin-11-yliden)tropan
• 3-(6H-Dibenzo[b,e]thiepin-11-ylidene)tropane
• 3-Dibenzo(b,e)thiepin-11(6H)-ylidene-1alphaH,5alphaH-tropane
• 3-Dibenzo(b,e)thiepin-11(6H)-ylidene-8-methyl-8-azabicyclo(3.2.1)octane
• 3-Dibenzo(b,e)thiepin-11(6H)-ylidenetropane
• 8-Azabicyclo(3.2.1)octane, 3-dibenzo(b,e)thiepin-11(6H)-ylidene-8-methyl-
• Dibenzo[b,e]thiepin, 8-azabicyclo[3.2.1]octane deriv.
• SD 1248-17 (as hydrochloride)
• Tropatepina
• Tropatepina [INN-Spanish]
• Tropatepine [INN:DCF]
• Tropatepinum
• Tropatepinum [INN-Latin]
• Unii-C27Hy5Rfu5
• 1αH,5αH-Tropane, 3-dibenzo[b,e]thiepin-11(6H)-ylidene-

8-Azabicyclo[3.2.1]octane, 3-dibenzo[b,e]thiepin-11(6H)-ylidene-8-methyl-

CAS: 27574-24-9

• Formula: C₂₂H₂₃NS
• Molecular weight: 333.4897

Tropatepine (Mixture of Diastereomers)

CAS: 27574-24-9

• Formula: C₂₂H₂₃NS
• Molecular weight: 333.49

Tropatepine-13C-d3

CAS: 27574-24-9

• Formula: CC₂₁H₂₀D₃NS
• Color and Shape: White To Off-White Solid
• Molecular weight: 337.50

Tropatepine

CAS: 27574-24-9

• Formula: C₂₂H₂₃NS
• Color and Shape: Neat
• Molecular weight: 333.49

Tropatepine-¹³CD₃

CAS: 27574-24-9

• Formula: CC₂₁D₃H₂₀NS
• Color and Shape: Neat
• Molecular weight: 337.501

Tropatepine

CAS: 27574-24-9

Tropatepine: oral anticholinergic, treats extrapyramidal symptoms, anti-Parkinson's.

• Formula: C₂₂H₂₃NS
• Color and Shape: Liquid
• Molecular weight: 333.49