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CAS 2757728-47-3

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  • KDX1381

    CAS:
    KDX1381 is a bivalent CK2α inhibitor with an IC50 of 17 nM and a KD of 54 nM. It demonstrates antitumor activity in murine 786-O and A375 xenograft models. Furthermore, when combined with a vascular endothelial growth factor receptor (VEGFR) inhibitor or DNA-damaging agents, KDX1381 enhances antitumor effects in mouse hepatocellular carcinoma and glioma models.
    Formula:C32H32F2N6O4S
    Color and Shape:Solid
    Molecular weight:634.70