HDAC6-IN-27 is a chemical compound that functions as an inhibitor of histone deacetylase 6 (HDAC6), an enzyme involved in various cellular processes, including gene expression, cell cycle regulation, and protein degradation. This compound is part of a broader class of HDAC inhibitors that have garnered interest for their potential therapeutic applications, particularly in cancer treatment and neurodegenerative diseases. HDAC6 specifically targets non-histone proteins, influencing pathways related to cell stress responses and immune regulation. The inhibition of HDAC6 can lead to increased acetylation of target proteins, which may enhance their stability and function. Additionally, HDAC6-IN-27 may exhibit selectivity for HDAC6 over other HDAC isoforms, which is crucial for minimizing side effects and improving therapeutic efficacy. As with many experimental compounds, further research is necessary to fully elucidate its pharmacological properties, mechanisms of action, and potential clinical applications.

HDAC6-IN-27

2758023-91-3: HDAC6-IN-27 is a chemical compound that functions as an inhibitor of histone deacetylase 6 (HDAC6), an enzyme involved in various cellular processes, including gene expression, cell cycle regulation, and protein degradation. This compound is part of a broader class of HDAC inhibitors that have garnered interest for their potential therapeutic applications, particularly in cancer treatment and neurodegenerative diseases. HDAC6 specifically targets non-histone proteins, influencing pathways related to cell stress responses and immune regulation. The inhibition of HDAC6 can lead to increased acetylation of target proteins, which may enhance their stability and function. Additionally, HDAC6-IN-27 may exhibit selectivity for HDAC6 over other HDAC isoforms, which is crucial for minimizing side effects and improving therapeutic efficacy. As with many experimental compounds, further research is necessary to fully elucidate its pharmacological properties, mechanisms of action, and potential clinical applications.

<p>HDAC6-IN-27 (compound 8C), an HDAC inhibitor, exhibits IC 50 values of 15.9 nM, 136.5 nM, and 6180.2 nM against HDAC6, HDAC8, and HDAC1, respectively. It also demonstrates potent antiparasitic effects [1].</p>

CAS 2758023-91-3

HDAC6-IN-27

HDAC6-IN-27

Ref: TM-T86553