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CAS 2759280-09-4

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  • WS-11

    CAS:
    <p>WS-11 is a non-covalent reversible inhibitor of BTK, with IC50 values of 3.9 nM for the wild-type and 2.2 nM for the C481S mutant BTK. In addition to strong hydrogen bonding, WS-11 also forms robust π-π interactions with PHE540, and p-π interactions with LYS430 within the active pocket.</p>
    Formula:C26H22FN9O2
    Color and Shape:Solid
    Molecular weight:511.51