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CAS 2760195-67-1

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  • SYHA1815
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    SYHA1815

    CAS:
    SYHA1815, an orally active RET inhibitor (IC50=0.9 nmol/L), demonstrates antitumor activity. It exhibits greater selectivity for RET over KDR (IC50=15.9 nmol/L). SYHA1815 operates by downregulating c-Myc, arresting the G1 cell cycle, and inhibiting RET-driven cell proliferation.
    Formula:C27H26ClF4N5O
    Color and Shape:Solid
    Molecular weight:547.98

    Ref: TM-T200124