CAS 2760329-44-8

2-Pyridinamine, 3,5-difluoro-N-[(3S,4S)-4-fluoro-3-piperidinyl]-6-[7-(1-methylethoxy)imidazo[1,2-a]pyridin-3-yl]-

Formula: C₂₀H₂₂F₃N₅O

Synonyms:

• 2-Pyridinamine, 3,5-difluoro-N-[(3S,4S)-4-fluoro-3-piperidinyl]-6-[7-(1-methylethoxy)imidazo[1,2-a]pyridin-3-yl]-

IRAK1/4/pan-FLT3 Kinase-IN-2

CAS: 2760329-44-8

IRAK1/4/pan-FLT3 Kinase-IN-2 (compound 27) is a potent dual inhibitor of IRAK1/4 and FLT3 with IC50 values of 10 nM, 0.7 nM, and < 0.5 nM, respectively. This compound enhances survival in mice models of acute myeloid leukemia.

Formula: C₂₀H₂₂F₃N₅O

Color and Shape: Solid

Molecular weight: 405.42

Ref: TM-T207286