CAS 2761767-18-2

GJG057

CAS: 2761767-18-2

GJG057 is a highly efficient and selective Leukotriene C4 synthase (LTC4S) inhibitor with an IC50 of 44 nM in human whole blood LTC4 release assays and oral activity. It demonstrates anti-inflammatory efficacy in a mouse asthma exacerbation model and can be used for the treatment of allergic inflammation.

Formula: C₂₁H₂₁F₅N₄O₂

Purity: 99.8%

Color and Shape: Solid

Molecular weight: 456.41

Ref: TM-T205247