CAS 2762296-44-4

2-Pyrimidinamine, N-[4-(4-ethyl-1-piperazinyl)-3-fluorophenyl]-5-fluoro-4-[1-(1-methylethyl)-1H-pyrazolo[4,3-b]pyridin-6-yl]-

Description:

2-Pyrimidinamine, N-[4-(4-ethyl-1-piperazinyl)-3-fluorophenyl]-5-fluoro-4-[1-(1-methylethyl)-1H-pyrazolo[4,3-b]pyridin-6-yl]- is a complex organic compound characterized by its multi-ring structure and various functional groups. It features a pyrimidine core, which is a six-membered aromatic ring containing two nitrogen atoms. The presence of a piperazine moiety contributes to its potential biological activity, often enhancing solubility and receptor binding. The fluorine substituents on the phenyl and pyrimidine rings may influence the compound's electronic properties and lipophilicity, potentially affecting its pharmacokinetics. Additionally, the isopropyl group attached to the pyrazolo-pyridine structure may enhance steric hindrance, impacting its interaction with biological targets. This compound is likely to be of interest in medicinal chemistry, particularly in the development of pharmaceuticals, due to its structural complexity and the presence of multiple functional groups that can interact with various biological pathways. Its specific properties, such as solubility, stability, and reactivity, would require empirical investigation to fully characterize its behavior in biological systems.

Formula: C₂₅H₂₈F₂N₈

Synonyms:

• FLT3/CDK4-IN-1
• 2-Pyrimidinamine, N-[4-(4-ethyl-1-piperazinyl)-3-fluorophenyl]-5-fluoro-4-[1-(1-methylethyl)-1H-pyrazolo[4,3-b]pyridin-6-yl]-

FLT3/CDK4-IN-1

CAS: 2762296-44-4

FLT3/CDK4-IN-1: Oral FLT3 (7 nM IC50) & CDK4 (11 nM IC50) inhibitor with strong in vivo anti-cancer properties.

Formula: C₂₅H₂₈F₂N₈

Color and Shape: Solid

Molecular weight: 478.54

Ref: TM-T63135