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CAS 2765058-89-5

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  • 10-SLF
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    10-SLF

    CAS:
    <p>10-SLF is a PROTAC FKBP12 degrader. It facilitates the formation of a ternary complex between FKBP12 and FBXW7-R465C, leading to the proteasomal degradation of FKBP12 in a FBXW7-R465C-dependent manner. 10-SLF selectively reduces FKBP12 levels in cells that express FBXW7-R465C.</p>
    Formula:C59H76Cl2N4O13
    Color and Shape:Solid
    Molecular weight:1120.16

    Ref: TM-T205612