CAS 2765449-10-1

2H-Imidazo[4,5-c]quinolin-2-one, 1-[(4S)-3,3-difluoro-1-methyl-4-piperidinyl]-1,3-dihydro-8-(6-methoxy-3-pyridinyl)-3-methyl-

Description:

2H-Imidazo[4,5-c]quinolin-2-one, 1-[(4S)-3,3-difluoro-1-methyl-4-piperidinyl]-1,3-dihydro-8-(6-methoxy-3-pyridinyl)-3-methyl- is a complex organic compound characterized by its unique bicyclic structure that incorporates both imidazole and quinoline moieties. This compound features a piperidine ring with difluoromethyl and methyl substituents, contributing to its potential biological activity. The presence of a methoxy group on the pyridine ring enhances its lipophilicity, which may influence its pharmacokinetic properties. The stereochemistry indicated by the (4S) configuration suggests specific spatial arrangements that can affect the compound's interaction with biological targets. Such compounds are often investigated for their potential therapeutic applications, particularly in the fields of medicinal chemistry and drug development. The CAS number 2765449-10-1 uniquely identifies this substance, facilitating its recognition in chemical databases and literature. Overall, this compound exemplifies the intricate design often found in drug candidates, combining multiple functional groups that may contribute to its efficacy and selectivity in biological systems.

Formula: C₂₃H₂₃F₂N₅O₂

Synonyms:

• 2H-Imidazo[4,5-c]quinolin-2-one, 1-[(4S)-3,3-difluoro-1-methyl-4-piperidinyl]-1,3-dihydro-8-(6-methoxy-3-pyridinyl)-3-methyl-

(S)-WSD0628

CAS: 2765449-10-1

(S)-WSD0628 is the S isomer of WSD0628 and serves as an ATM inhibitor, effectively suppressing ATM phosphorylation in MCF-7 cells with an IC50 of less than 100 nM. This compound also demonstrates radiosensitizing activity and is capable of penetrating the blood-brain barrier.

Formula: C₂₃H₂₃F₂N₅O₂

Color and Shape: Solid

Molecular weight: 439.458

Ref: TM-T205268