CymitQuimica logo

CAS 276696-61-8

:

Rp-8-[(4-Chlorophenyl)thio]-guanosine-cyclic 3′,5′-hydrogen phosphorothioate triethylammonium salt

Description:
Rp-8-[(4-Chlorophenyl)thio]-guanosine-cyclic 3′,5′-hydrogen phosphorothioate triethylammonium salt is a synthetic nucleotide analog that serves as a potent inhibitor of cyclic nucleotide phosphodiesterases. This compound is characterized by its unique structure, which includes a guanosine base linked to a cyclic phosphorothioate moiety, enhancing its stability and biological activity compared to natural nucleotides. The presence of the 4-chlorophenylthio group contributes to its specificity and potency in modulating signaling pathways involving cyclic guanosine monophosphate (cGMP). As a triethylammonium salt, it exhibits solubility in aqueous solutions, making it suitable for various biochemical assays and cellular studies. This compound is primarily used in research settings to investigate the roles of cGMP in cellular processes, including vasodilation, neurotransmission, and cell proliferation. Its ability to inhibit phosphodiesterases allows for the accumulation of cGMP, thereby amplifying its physiological effects. Overall, Rp-8-[(4-Chlorophenyl)thio]-guanosine-cyclic 3′,5′-hydrogen phosphorothioate triethylammonium salt is a valuable tool in pharmacological and biochemical research.
Formula:C22H30ClN6O6PS2
Synonyms:
  • 8-(4-CHLOROPHENYLTHIO)-GUANOSINE 3',5'-CYCLIC MON...
  • Rp-8-[(4-Chlorophenyl)thio]-guanosine-cyclic 3′,5′-hydrogen phosphorothioate triethylammonium salt
  • Rp-8-CPT-cGMPS
  • 8-(4-Chlorophenylthio)-guanosine 3',5'-cyclic monophosphorothioate, Rp Isomer triethylammonium salt >=98% (HPLC), solid
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 1 products.
  • Rp-8-pCPT-cGMPS
    Biosynth
    + Info

    Rp-8-pCPT-cGMPS

    CAS:
    Rp-8-pCPT-cGMPS is a chemical compound that acts as an inhibitor of the phosphodiesterase enzyme and can be used to increase the concentration of cyclic guanosine monophosphate (cGMP) in heart muscle cells. It is not an activator and does not bind to the cgmp-dependent protein kinase. Rp-8-pCPT-cGMPS binds to the cgmp-dependent protein kinase, inhibiting its activity. This inhibition of cgmp-dependent protein kinase leads to increased levels of cGMP, which results in a rise in intracellular calcium levels and an increase in cardiac contractility.
    Formula:C22H30ClN6O6PS2
    Purity:Min. 95%
    Molecular weight:605.1 g/mol

    Ref: 3D-BLA69661

    1mg
    1,402.00€