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CAS 2767-80-8

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Tris(hydroxymethyl)phosphine

Description:
Tris(hydroxymethyl)phosphine (THP) is an organophosphorus compound characterized by its three hydroxymethyl groups attached to a phosphorus atom. It is a colorless to pale yellow liquid at room temperature and is known for its high solubility in water and various organic solvents. THP is primarily used as a reducing agent in organic synthesis, particularly in the reduction of carbonyl compounds and in the preparation of phosphine oxides. Its structure allows it to act as a bidentate ligand in coordination chemistry, forming complexes with transition metals. Additionally, THP exhibits low toxicity compared to other phosphines, making it a safer alternative in laboratory settings. The compound is stable under normal conditions but should be handled with care due to its potential reactivity with strong oxidizing agents. Overall, tris(hydroxymethyl)phosphine is valued for its versatility in synthetic chemistry and its role in various chemical transformations.
Formula:C3H9O3P
InChI:InChI=1/C3H9O3P/c4-1-7(2-5)3-6/h4-6H,1-3H2
InChI key:InChIKey=JMXMXKRNIYCNRV-UHFFFAOYSA-N
SMILES:P(CO)(CO)CO
Synonyms:
  • 1,1′,1′′-Phosphinidynetris[methanol]
  • Methanol, 1,1',1''-phosphinidynetris-
  • Methanol, 1,1′,1′′-phosphinidynetris-
  • Methanol, phosphinidynetri-
  • Methanol, phosphinidynetri- (7CI,8CI)
  • Methanol, phosphinidynetris-
  • Phosphanetriyltrimethanol
  • Phosphine, tris(hydroxymethyl)-
  • Phosphinidynetrimethanol
  • Phosphinidynetrismethanol
  • See more synonyms
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