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CAS 2768099-61-0

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  • KRAS G12D inhibitor 25
    Targetmol
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    KRAS G12D inhibitor 25

    CAS:
    KRAS G12D inhibitor 25 (Compound 148) acts as an inhibitor for KRAS G12C and HSP90α, displaying IC50 values of <0.1 μM and 0.1-1 μM respectively. Additionally, it suppresses the proliferation of MIA PaCa-2 and NCI-H358 cell lines, with EC50 values of <0.1 μM and 0.1-1 μM correspondingly. This compound also promotes the degradation of ERBB2, exhibiting a DC50 of 0.1-1 μM.
    Formula:C56H62ClN11O6
    Color and Shape:Solid
    Molecular weight:1020.62

    Ref: TM-T201006