CAS 2768514-05-0

1H-Indene-5-carboxylic acid, 3-[[[5-[4-[(dimethylamino)carbonyl]-3-hydroxyphenyl]-3-isoxazolyl]carbonyl]amino]-2,3-dihydro-, (3R)-

Description:

1H-Indene-5-carboxylic acid, 3-[[[5-[4-[(dimethylamino)carbonyl]-3-hydroxyphenyl]-3-isoxazolyl]carbonyl]amino]-2,3-dihydro-, (3R)- is a complex organic compound characterized by its unique structural features, including an indene ring fused with a carboxylic acid group and various functional groups such as isoxazole and dimethylamino moieties. This compound exhibits properties typical of carboxylic acids, including acidity and the ability to form hydrogen bonds, which can influence its solubility and reactivity. The presence of the dimethylamino group suggests potential basicity, while the hydroxyphenyl group may contribute to its ability to engage in hydrogen bonding and π-π stacking interactions. The stereochemistry indicated by the (3R) designation implies specific spatial arrangements that can affect the compound's biological activity and interactions with other molecules. Overall, this compound's intricate structure may confer unique pharmacological properties, making it of interest in medicinal chemistry and drug development.

Formula: C₂₃H₂₁N₃O₆

Synonyms:

• 1H-Indene-5-carboxylic acid, 3-[[[5-[4-[(dimethylamino)carbonyl]-3-hydroxyphenyl]-3-isoxazolyl]carbonyl]amino]-2,3-dihydro-, (3R)-

PFI-6-COOH

CAS: 2768514-05-0

PFI-6-COOH (Compound 18) is a ligand for the eleven-nineteen leukemia (ENL) protein, and is utilized in the synthesis of the ENL PROTAC degrader MS41.

Formula: C₂₃H₂₁N₃O₆

Color and Shape: Solid

Molecular weight: 435.43

Ref: TM-T200809