Trt-Cys(Trt)-OH, also known as Trityl-Cysteine, is a protected form of the amino acid cysteine, which is characterized by the presence of a trityl (Trt) protecting group on the thiol (-SH) side chain. This protection is crucial in peptide synthesis, as it prevents unwanted reactions of the thiol group during coupling reactions. The compound features a primary amine group (-NH2) and a carboxylic acid group (-COOH), typical of amino acids, allowing it to participate in peptide bond formation. The trityl group enhances the stability and solubility of the molecule, making it easier to handle in various chemical reactions. Trt-Cys(Trt)-OH is often utilized in the synthesis of peptides and proteins, particularly in solid-phase peptide synthesis, where selective deprotection of the trityl group can be achieved under mild acidic conditions. Its CAS number, 27686-50-6, is a unique identifier that facilitates the identification and procurement of this compound in chemical databases and research settings.

Trt-Cys(Trt)-OH

27686-50-6: Trt-Cys(Trt)-OH, also known as Trityl-Cysteine, is a protected form of the amino acid cysteine, which is characterized by the presence of a trityl (Trt) protecting group on the thiol (-SH) side chain. This protection is crucial in peptide synthesis, as it prevents unwanted reactions of the thiol group during coupling reactions. The compound features a primary amine group (-NH2) and a carboxylic acid group (-COOH), typical of amino acids, allowing it to participate in peptide bond formation. The trityl group enhances the stability and solubility of the molecule, making it easier to handle in various chemical reactions. Trt-Cys(Trt)-OH is often utilized in the synthesis of peptides and proteins, particularly in solid-phase peptide synthesis, where selective deprotection of the trityl group can be achieved under mild acidic conditions. Its CAS number, 27686-50-6, is a unique identifier that facilitates the identification and procurement of this compound in chemical databases and research settings.

<p>Trt-Cys(Trt)-OH is a selective dicyclohexyl carbodiimide reagent for the synthesis of amides from carboxylic acids. It is used as an intermediate in the synthesis of glutathione and other nitrogen-containing compounds. Trt-Cys(Trt)-OH reacts with hydrochloric acid to form a salt, which can be saponified to release the desired product. The hydrochloric acid converts the ester into a carboxylic acid, while the amine group on the glycine reacts with the carboxylic acid to form an amide. Trityl is also produced during this reaction, which can be removed by reduction with hydrogen gas and palladium on charcoal.</p>

CAS 27686-50-6

Trt-Cys(Trt)-OH

Trt-Cys(Trt)-OH

Ref: IN-DA002UFQ

Trt-Cys(Trt)-OH

Ref: 3D-FT107842