CAS 27686-84-6

Masoprocol

Description:

Masoprocol, also known as 2-(4-methylphenyl)-4-(3-methylphenyl)-1,3-thiazole-5-carboxylic acid, is a synthetic compound primarily recognized for its role in dermatological applications, particularly as a topical agent for treating skin conditions. It exhibits anti-inflammatory and antioxidant properties, making it beneficial in managing conditions like psoriasis and other inflammatory skin disorders. Masoprocol functions by inhibiting the activity of certain enzymes involved in the inflammatory process, thereby reducing redness and irritation. The compound is characterized by its thiazole ring structure, which contributes to its biological activity. It is typically formulated in creams or ointments for direct application to the skin. Safety and efficacy profiles have been established through clinical studies, although, like any pharmaceutical agent, it may have potential side effects that require consideration. Overall, masoprocol represents a valuable option in dermatological therapy, particularly for patients seeking alternatives to traditional corticosteroids.

Formula: C₁₈H₂₂O₄

InChI: InChI=1/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3/t11-,12+

InChI key: InChIKey=HCZKYJDFEPMADG-TXEJJXNPNA-N

SMILES: C([C@@H]([C@@H](CC1=CC(O)=C(O)C=C1)C)C)C2=CC(O)=C(O)C=C2

Synonyms:

• 1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-
• 1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (R*,S*)-
• 1,2-Benzenediol, 4,4′-[(2R,3S)-2,3-dimethyl-1,4-butanediyl]bis-, rel-
• 2,3-Bis(3,4-dihydroxybenzyl)butane
• 248-606-6
• 4,4'-(2,3-Dimethyl-1,4-butanediyl)di(1,2-benzenediol)
• 4,4'-(2,3-Dimethylbutane-1,4-diyl)dibenzene-1,2-diol
• 4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol
• Actinex
• Chx 100
• Pyrocatechol, 4,4′-(2,3-dimethyltetramethylene)di-, meso-
• meso-NDGA
• meso-Nordihydroguaiaretic acid
• rel-4,4′-[(2R,3S)-2,3-Dimethyl-1,4-butanediyl]bis[1,2-benzenediol]
• (R*,S*)-4,4'-(2,3-dimethylbutane-1,4-diyl)bispyrocatechol
• 4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]benzene-1,2-diol
• NORHYDROGUAIARETICACID
• 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol
• Masoprocol(nordihydroguaiaretic)
• 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyrocatechol
• 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]benzene-1,2-diol
• meso-4，4'-(2，3- Dimethyltetramethylene)dipyrocatechol
• 4,4'-((2R,3S)-2,3-DiMethylbutane-1,4-diyl)bis(benzene-1,2-diol)
• rel-4,4'-((2R,3S)-2,3-Dimethylbutane-1,4-diyl)bis(benzene-1,2-diol)

4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol

CAS: 27686-84-6

Formula: C₁₈H₂₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 302.3649

Ref: IN-DA002UFP

Masoprocol

CAS: 27686-84-6

Masoprocol is a topical antineoplastic agent, which is a synthetic derivative of the naturally occurring catechol compound. Its source is primarily the leaves of the creosote bush, *Larrea tridentata*, an evergreen shrub prevalent in desert regions. The compound functions by inhibiting lipoxygenase activity, thereby impeding arachidonic acid metabolism, and ultimately reducing the synthesis of inflammatory mediators and tumor-promoting compounds. Furthermore, Masoprocol exhibits antioxidative properties, contributing to its therapeutic effects.

Formula: C₁₈H₂₂O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 302.36 g/mol

Ref: 3D-XN163193

Masoprocol

CAS: 27686-84-6

Masoprocol (meso-Nordihydroguaiaretic acid) is a LOX inhibitor with anticancer and antihyperglycemic activity.

Formula: C₁₈H₂₂O₄

Purity: 99.76%

Color and Shape: Solid

Molecular weight: 302.37

Ref: TM-T60692