CAS 27699-51-0
:cyclohexanecarbonyl isothiocyanate
Description:
Cyclohexanecarbonyl isothiocyanate is an organic compound characterized by the presence of both a cyclohexane ring and an isothiocyanate functional group. Its molecular structure features a carbonyl group attached to a cyclohexane ring, with an isothiocyanate (-N=C=S) substituent. This compound is typically a colorless to pale yellow liquid with a pungent odor, indicative of the isothiocyanate group. It is known for its reactivity, particularly in nucleophilic addition reactions, and can serve as a versatile intermediate in organic synthesis, especially in the preparation of thioureas and other sulfur-containing compounds. Cyclohexanecarbonyl isothiocyanate is soluble in organic solvents but has limited solubility in water. As with many isothiocyanates, it may exhibit biological activity, including potential antimicrobial properties. Safety precautions should be taken when handling this compound, as it can be irritating to the skin, eyes, and respiratory system. Proper storage in a cool, dry place away from incompatible substances is essential to maintain its stability and prevent degradation.
Formula:C8H11NOS
InChI:InChI=1/C8H11NOS/c10-8(9-6-11)7-4-2-1-3-5-7/h7H,1-5H2
SMILES:C1CCC(CC1)C(=O)N=C=S
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Found 2 products.
Cyclohexanecarbonyl isothiocyanate
CAS:Cyclohexanecarbonyl isothiocyanate (CHITC) is a reactive thiocyanation agent that can be used to modify proteins. CHITC reacts with amines in the presence of an organocatalyst to form a new molecule, N-isothiocyanato-L-cysteine. This reaction produces reactive intermediates that react with other amine groups on the same protein or with other proteins present in solution. This process has been shown to lead to the selective modification of proteins without affecting the biological activity of these proteins.Formula:C8H11NOSPurity:Min. 95%Molecular weight:169.25 g/mol
