CAS 2770-01-6

4-Chloro-1H-imidazo[4,5-c]pyridine

Description:

4-Chloro-1H-imidazo[4,5-c]pyridine is a heterocyclic compound characterized by its fused imidazole and pyridine rings, which contribute to its unique chemical properties. This compound features a chlorine substituent at the 4-position of the imidazole ring, influencing its reactivity and potential applications. It is typically a solid at room temperature and exhibits moderate solubility in organic solvents, while being less soluble in water due to its aromatic structure. The presence of both nitrogen atoms in the rings enhances its basicity and potential for coordination with metal ions. 4-Chloro-1H-imidazo[4,5-c]pyridine is of interest in medicinal chemistry, particularly for its potential biological activities, including antimicrobial and anticancer properties. Its structural characteristics allow for various synthetic modifications, making it a valuable intermediate in the development of pharmaceuticals and agrochemicals. Safety data indicates that, like many chlorinated compounds, it should be handled with care due to potential toxicity and environmental concerns.

Formula: C₆H₄ClN₃

InChI: InChI=1/C6H4ClN3/c7-6-5-4(1-2-8-6)9-3-10-5/h1-3H,(H,9,10)

SMILES: c1cnc(c2c1nc[nH]2)Cl

Synonyms:

• 1H-Imidazo[4,5-c]pyridine, 4-chloro-

3H-Imidazo[4,5-c]pyridine, 4-chloro-

CAS: 2770-01-6

Formula: C₆H₄ClN₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 153.5691

Ref: IN-DA002UIK

4-Chloro-1H-imidazo[4,5-c]pyridine

CAS: 2770-01-6

Purity: >95%

Molecular weight: 153.569

Ref: FT-C12908

4-Chloro-1H-imidazo[4,5-c]pyridine

CAS: 2770-01-6

4-Chloro-1H-imidazo[4,5-c]pyridine

Formula: C₆H₄ClN₃

Purity: 98%

Color and Shape: white solid

Molecular weight: 153.57g/mol

Ref: 54-OR302509

4-Chloro-1H-imidazo[4,5-c]pyridine

CAS: 2770-01-6

Formula: C₆H₄ClN₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 153.57

Ref: 10-F079946

4-Chloro-1H-imidazo[4,5-c]pyridine

Controlled Product

CAS: 2770-01-6

Applications 4-Chloro-1H-imidazo[4,5-c]pyridine is used as a reagent in the synthesis of 3-bromo-3-deazaneplanocin and 3-bromo-3-deazaaristeromycin, compounds which exhibit antiviral activity.
References Liu, Ch., et al.: Bioorg. Med. Chem. Lett., 22, 5182 (2012)

Formula: C₁₁H₁₆N₅O·F₆P

Color and Shape: Neat

Molecular weight: 379.242

Ref: TR-C367595

4-Chloro-1H-imidazo[4,5-c]pyridine

CAS: 2770-01-6

4-Chloro-1H-imidazo[4,5-c]pyridine (4CI) is a nucleoside analog that inhibits the replication of RNA and DNA. It has significant inhibitory activity against herpes simplex virus type 1 and human immunodeficiency virus type 1 (HIV-1). 4CI inhibits the synthesis of adenosine, an important component in the synthesis of RNA and DNA. This drug also has antiviral properties against influenza A and B viruses. 4CI's effect on plasma cholesterol levels is thought to be due to inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase.

Formula: C₆H₄ClN₃

Purity: Min. 95%

Color and Shape: Off-White Solid

Molecular weight: 153.57 g/mol

Ref: 3D-FC32403