The chemical substance known as "5-[[4-[1-(Ethylsulfonyl)-1H-indol-3-yl]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-N,N-dimethyl-1H-indole-1-ethanamine" with CAS number 2770009-06-6 is a complex organic compound characterized by its multi-ring structure, which includes indole and pyrimidine moieties. This compound features a trifluoromethyl group, which is known to enhance lipophilicity and biological activity. The presence of an ethylsulfonyl group suggests potential for interactions with biological targets, possibly influencing its pharmacological properties. The dimethylamino group indicates basicity, which may affect solubility and reactivity. Overall, this compound is likely to exhibit significant biological activity, making it of interest in medicinal chemistry and drug development. Its intricate structure suggests potential for specific interactions with biological macromolecules, which could be explored for therapeutic applications. However, detailed studies would be necessary to fully understand its properties, including its stability, solubility, and biological efficacy.

5-[[4-[1-(Ethylsulfonyl)-1H-indol-3-yl]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-N,N-dimethyl-1H-indole-1-ethanamine

2770009-06-6: The chemical substance known as "5-[[4-[1-(Ethylsulfonyl)-1H-indol-3-yl]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-N,N-dimethyl-1H-indole-1-ethanamine" with CAS number 2770009-06-6 is a complex organic compound characterized by its multi-ring structure, which includes indole and pyrimidine moieties. This compound features a trifluoromethyl group, which is known to enhance lipophilicity and biological activity. The presence of an ethylsulfonyl group suggests potential for interactions with biological targets, possibly influencing its pharmacological properties. The dimethylamino group indicates basicity, which may affect solubility and reactivity. Overall, this compound is likely to exhibit significant biological activity, making it of interest in medicinal chemistry and drug development. Its intricate structure suggests potential for specific interactions with biological macromolecules, which could be explored for therapeutic applications. However, detailed studies would be necessary to fully understand its properties, including its stability, solubility, and biological efficacy.

EGFR mutant-IN-2

<p>EGFR mutant-IN-2 (Compound D51) is an inhibitor of EGFR mutants, specifically targeting EGFR L858R/T790M/C797S and EGFR del19/T790M/C797S mutants with IC50 values of 14 nM and 62 nM, respectively. This compound exhibits favorable pharmacokinetic (PK) parameters, safety properties, in vivo stability, and demonstrates antitumor activity [1].</p>

CAS 2770009-06-6

5-[[4-[1-(Ethylsulfonyl)-1H-indol-3-yl]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-N,N-dimethyl-1H-indole-1-ethanamine

EGFR mutant-IN-2

Ref: 54-PC1006535

EGFR mutant-IN-2

Ref: TM-T86344