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CAS 2771955-09-8

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  • PF-7006
    Targetmol
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    PF-7006

    CAS:
    <p>PF-7006, an Mps1 kinase inhibitor, exhibits a Ki value of 0.27 nM and an IC50 value of 2.5 nM. It disrupts cell cycle checkpoints by inhibiting the catalytic activity of Mps1, reduces histone H3 levels, and shortens the duration of mitosis, thereby inducing apoptosis (Apoptosis) in cancer cells. When used in combination with Palbociclib, the tolerance of cancer cells to PF-7006 is enhanced. PF-7006 is applicable for research on breast cancer.</p>
    Formula:C22H26N8O2
    Color and Shape:Solid
    Molecular weight:434.49

    Ref: TM-T200142