CAS 277302-47-3

Tip-39

Description:

Tip-39, with the CAS number 277302-47-3, is a synthetic peptide that acts as a selective agonist for the neuropeptide Y (NPY) receptor system. This compound is characterized by its ability to influence various physiological processes, including appetite regulation, anxiety, and stress response. Tip-39 is known for its specific interaction with the Y1 receptor subtype, which plays a crucial role in mediating the effects of neuropeptide Y in the central nervous system. The peptide's structure typically includes a sequence of amino acids that confer its biological activity, stability, and receptor selectivity. Research into Tip-39 has highlighted its potential therapeutic applications, particularly in the fields of neuropharmacology and metabolic disorders. However, as with many peptides, its stability and bioavailability can be challenges for therapeutic use, necessitating further studies to optimize its delivery and efficacy. Overall, Tip-39 represents a significant interest in the study of neuropeptides and their roles in human health and disease.

TIP-39

CAS: 277302-47-3

Tuberoinfundibular peptide, TIP-39, originally isolated from bovine hypothalamus was found to be a potent and selective agonist of the pTH2 receptor which regulates pituitary hormone secretion and spinal cord regions involved in pain perception. Synthetic TIP-39 activated the human and rat pTH2 receptors with EC₅₀ of 0.5 ± 0.12 nM and 0.8 ± 0.3 nM, respectively. TIP-39 was much more potent than pTH (EC₅₀ = 49 ± 23 nM) at the rat pTH2 receptor. The discovery of TIP-39 provides an important tool for the investigation of the pTH2 receptor functions inside and outside the nervous system.

Formula: C₂₀₂H₃₂₅N₆₁O₅₄S

Purity: > 98%

Color and Shape: White

Molecular weight: 4504.25

Ref: 01-4033516

TIP 39, Tuberoinfundibular Neuropeptide

CAS: 277302-47-3

TIP39 is a synthetic neuropeptide agonist for human and rat PTH2 receptors from the hypothalamus.

Formula: C₂₀₂H₃₂₅N₆₁O₅₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 4504.2

Ref: TM-TP1688

TIP-39 trifluoroacetate salt

CAS: 277302-47-3

Please enquire for more information about TIP-39 trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₂₀₂H₃₂₅N₆₁O₅₄S

Purity: Min. 95%

Molecular weight: 4,504.19 g/mol

Ref: 3D-FT109386