CAS 2781912-10-3

α-[4-(Difluoromethyl)-6-[2-[4-[[4-(hydroxymethyl)-1-piperidinyl]methyl]phenyl]ethynyl]-7-methyl-2H-indazol-2-yl]-6′,7′-dihydro-N-2-thiazolylspiro[cyclopropane-1,5′-[5H]pyrrolo[1,2-c]imidazole]-1′-acetamide

Formula: C₃₇H₃₇F₂N₇O₂S

Synonyms:

• EGFR-IN-102
• α-[4-(Difluoromethyl)-6-[2-[4-[[4-(hydroxymethyl)-1-piperidinyl]methyl]phenyl]ethynyl]-7-methyl-2H-indazol-2-yl]-6′,7′-dihydro-N-2-thiazolylspiro[cyclopropane-1,5′-[5H]pyrrolo[1,2-c]imidazole]-1′-acetamide

EGFR-IN-102

CAS: 2781912-10-3

EGFR-IN-102 (compound 6), an orally active EGFR inhibitor, demonstrates an IC 50 of 2 nM and is utilized for research in non-small-cell lung cancer [1].

Formula: C₃₇H₃₇F₂N₇O₂S

Molecular weight: 681.80

Ref: TM-T86356