CymitQuimica logo

CAS 27821-54-1

:

Thymidine 5′-(tetrahydrogen triphosphate), sodium salt (1:3)

Description:
Thymidine 5′-(tetrahydrogen triphosphate), sodium salt (1:3), commonly referred to as TTP, is a nucleotide triphosphate that plays a crucial role in cellular metabolism and DNA synthesis. It is a derivative of thymidine, which is one of the four nucleosides that make up DNA. The compound features a ribose sugar, a thymine base, and three phosphate groups, which are responsible for its high-energy properties. The sodium salt form indicates that sodium ions are associated with the triphosphate, enhancing its solubility in aqueous solutions. TTP is essential for DNA polymerase activity during DNA replication and repair processes, serving as a substrate for the incorporation of thymidine into the growing DNA strand. Its stability and reactivity are influenced by the presence of the triphosphate groups, which can undergo hydrolysis to release energy. In laboratory settings, TTP is often utilized in various biochemical assays, including polymerase chain reactions (PCR) and other nucleic acid amplification techniques, due to its ability to facilitate the synthesis of DNA.
Formula:C10H17N2O14P3·3Na
InChI:InChI=1S/C10H17N2O14P3.3Na/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(24-8)4-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h3,6-8,13H,2,4H2,1H3,(H,19,20)(H,21,22)(H,11,14,15)(H2,16,17,18);;;/t6-,7+,8+;;;/m0.../s1
InChI key:InChIKey=KAGDVGHPCCXAPY-SPSULGLQSA-N
SMILES:O=C1N([C@@H]2O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@@H](O)C2)C=C(C)C(=O)N1.[Na]
Synonyms:
  • 2'-Deoxythymidine-5'-triphosphate,Trisodium Salt
  • 2,4(1H,3H)-pyrimidinedione, 1-[2-deoxy-5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]pentofuranosyl]-5-methyl-, sodium salt (1:3)
  • Thymidine 5'-(tetrahydrogen triphosphate), trisodium salt
  • Thymidine 5′-(tetrahydrogen triphosphate), sodium salt (1:3)
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 7 products.