CAS 27821-54-1

Thymidine 5′-(tetrahydrogen triphosphate), sodium salt (1:3)

Description:

Thymidine 5′-(tetrahydrogen triphosphate), sodium salt (1:3), commonly referred to as TTP, is a nucleotide triphosphate that plays a crucial role in cellular metabolism and DNA synthesis. It is a derivative of thymidine, which is one of the four nucleosides that make up DNA. The compound features a ribose sugar, a thymine base, and three phosphate groups, which are responsible for its high-energy properties. The sodium salt form indicates that sodium ions are associated with the triphosphate, enhancing its solubility in aqueous solutions. TTP is essential for DNA polymerase activity during DNA replication and repair processes, serving as a substrate for the incorporation of thymidine into the growing DNA strand. Its stability and reactivity are influenced by the presence of the triphosphate groups, which can undergo hydrolysis to release energy. In laboratory settings, TTP is often utilized in various biochemical assays, including polymerase chain reactions (PCR) and other nucleic acid amplification techniques, due to its ability to facilitate the synthesis of DNA.

Formula: C₁₀H₁₇N₂O₁₄P₃·3Na

InChI: InChI=1S/C10H17N2O14P3.3Na/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(24-8)4-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h3,6-8,13H,2,4H2,1H3,(H,19,20)(H,21,22)(H,11,14,15)(H2,16,17,18);;;/t6-,7+,8+;;;/m0.../s1

InChI key: InChIKey=KAGDVGHPCCXAPY-SPSULGLQSA-N

SMILES: O=C1N([C@@H]2O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@@H](O)C2)C=C(C)C(=O)N1.[Na]

Synonyms:

• 2'-Deoxythymidine-5'-triphosphate,Trisodium Salt
• 2,4(1H,3H)-pyrimidinedione, 1-[2-deoxy-5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]pentofuranosyl]-5-methyl-, sodium salt (1:3)
• Thymidine 5'-(tetrahydrogen triphosphate), trisodium salt
• Thymidine 5′-(tetrahydrogen triphosphate), sodium salt (1:3)

Thymidine 5'-(tetrahydrogen triphosphate), sodium salt (1:3)

CAS: 27821-54-1

Formula: C₁₈H₁₆O₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 312.3166

Ref: IN-DA002UUQ

5''-DTTP Na3

CAS: 27821-54-1

Formula: C₁₀H₁₄N₂Na₃O₁₄P₃

Purity: ≥ 98.0%

Color and Shape: White powder

Molecular weight: 548.12

Ref: 7W-GN3606

Deoxythymidine-5'-triphosphate trisodium

CAS: 27821-54-1

Deoxythymidine-5'-triphosphate trisodium

Purity: ≥98%

Molecular weight: 548.11g/mol

Ref: 54-BUP11146

2'-Deoxythymidine-5'-triphosphate trisodium salt

CAS: 27821-54-1

2'-Deoxythymidine-5'-triphosphate trisodium salt

Formula: C₁₀H₁₄N₂O₁₄P₃·3Na

Purity: 99% (Typical Value in Batch COA)

Color and Shape: white powder

Molecular weight: 548.11g/mol

Ref: 54-BID6623

Deoxythymidine-5'-triphosphate trisodium

CAS: 27821-54-1

dTTP trisodium salt, a natural deoxynucleotide for DNA synthesis by DNA polymerase and reverse transcriptase.

Formula: C₁₀H₁₄N₂Na₃O₁₄P₃

Purity: 97.47%

Color and Shape: Solid

Molecular weight: 548.11

Ref: TM-T9086

Thymidine-5'-triphosphate trisodium

CAS: 27821-54-1

Thymidine-5'-triphosphate or dTTP, is a nucleotide used by the cell to synthesize DNA molecules. Thymidine-5'-triphosphate is used in molecular biology techniques and assays as a substrate of the enzyme DNA polymerase, e.g. polymerase chain reaction (PCR), DNA sequencing, pyrosequencing reactions. Salt form of thymidine-5'-triphosphate has been used in a newly developed detection system for SARS-CoV-2 that combines bioluminescence in real-time (BART) with reverse-transcriptase loop-mediated amplification (RT-LAMP).

Formula: C₁₀H₁₇N₂O₁₄P₃•Na₃

Purity: (%) Min. 90%

Color and Shape: White Powder

Molecular weight: 551.14 g/mol

Ref: 3D-NT05748

Deoxythymidine-5′-triphosphate (trisodium)

CAS: 27821-54-1

Purity: 98%

Molecular weight: 548.113

Ref: 10-F987456