CAS 2784-73-8

6-Acetylmorphine

Description:

6-Acetylmorphine is a semi-synthetic opioid derived from morphine, characterized by the addition of an acetyl group at the 6-position of the morphine molecule. This modification enhances its lipophilicity, allowing for rapid penetration across the blood-brain barrier, which contributes to its potent analgesic and euphoric effects. It is typically encountered in the context of illicit drug use, as it is a metabolite of heroin, and is known for its high potential for addiction and abuse. The substance is classified as a controlled substance in many jurisdictions due to its psychoactive properties. In terms of physical characteristics, 6-acetylmorphine is usually found as a white to off-white crystalline powder, and it is soluble in organic solvents. Its chemical formula is C13H17NO3, and it has a molecular weight that reflects its complex structure. Due to its pharmacological effects, 6-acetylmorphine is of significant interest in both medical and forensic fields, particularly in studies related to opioid addiction and overdose.

Formula: C₁₉H₂₁NO₄

InChI: InChI=1S/C19H21NO4/c1-10(21)23-15-6-4-12-13-9-11-3-5-14(22)17-16(11)19(12,18(15)24-17)7-8-20(13)2/h3-6,12-13,15,18,22H,7-9H2,1-2H3/t12-,13+,15-,18-,19-/m0/s1

InChI key: InChIKey=JJGYGPZNTOPXGV-SSTWWWIQSA-N

SMILES: O(C(C)=O)[C@@H]1[C@]2([C@]34C=5C(O2)=C(O)C=CC5C[C@]([C@@]3(C=C1)[H])(N(C)CC4)[H])[H]

Synonyms:

• (5Alpha,6Alpha)-3-Hydroxy-17-Methyl-7,8-Didehydro-4,5-Epoxymorphinan-6-Yl Acetate
• 6-Acetylmorphine
• 6-Mam
• 6-Monoacetylmorphine
• 6-O-Acetylmorphine
• 6-O-Monoacetylmorphine
• 7,8-Didehydro-4,5alpha-epoxy-17-methylmorphinan-3,6alpha-diol 6-acetate
• Monoacetylmorphine
• Morphinan-3,6-alpha-diol, 7,8-didehydro-4,5-alpha-epoxy-17-methyl-, 6-acetate
• Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl- (5α,6α)-, 6-acetate
• Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl-, (5alpha,6alpha)-, 6-acetate
• Morphinan-3,6α-diol, 7,8-didehydro-4,5α-epoxy-17-methyl-, 6-acetate
• Morphine 6-acetate
• O(sup 6)-Monoacetylmorphine
• O⁶-Acetylmorphine

6-Acetylmorphine 1.0 mg/ml in Acetonitrile

Controlled Product

CAS: 2784-73-8

Color and Shape: Colourless

Ref: 61-AMP0037.14-11

6-Acetylmorphine

Controlled Product

CAS: 2784-73-8

Color and Shape: Neat

Ref: 61-FOR0037.14

6-Acetylmorphine 0.1 mg/ml in Acetonitrile

Controlled Product

CAS: 2784-73-8

Color and Shape: Single Solution

Ref: 61-AMP0037.14-12

6-Acetylmorphine

Controlled Product

CAS: 2784-73-8

Formula: C₁₉H₂₁NO₄

Color and Shape: Neat

Molecular weight: 327.374

Ref: 86-MM0037.14

6-Acetyl Morphine

Controlled Product

CAS: 2784-73-8

Applications A metabolite of Heroin (H281180). Controlled substance.
References Oldendorf, W., et al.: Science, 178, 984 (1972), Selley, D., et al.: Biochem. Pharmacol., 62, 447 (2001), Girardin, F., et al.: Clin. Pharmacol. Ther., 74, 341 (2003), Ferrari, A., et al.: Pharmacol. Res., 50, 551 (2004),

Formula: C₁₉H₂₁NO₄

Color and Shape: White To Light Beige

Molecular weight: 327.374

Ref: TR-A186900

6-Acetyl Morphine (100 ug/mL in Acetonitrile)

Controlled Product

CAS: 2784-73-8

Formula: C₁₉H₂₁NO₄

Color and Shape: Single Solution

Molecular weight: 327.374

Ref: TR-KIT1460

6-Acetyl Morphine (1 mg/ml in Acetonitrile)

Controlled Product

CAS: 2784-73-8

Formula: C₁₉H₂₁NO₄

Color and Shape: Single Solution

Molecular weight: 327.374

Ref: TR-KIT2730