CAS 27867-05-6

5-{[(2R)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3,4-dihydronaphthalen-1(2H)-one hydrochloride

Description:

5-{[(2R)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3,4-dihydronaphthalen-1(2H)-one hydrochloride, with the CAS number 27867-05-6, is a chemical compound characterized by its complex structure, which includes a naphthalene core substituted with a hydroxyl group and an ether linkage. This compound features a tert-butylamino group, contributing to its potential biological activity and solubility properties. The presence of the hydrochloride salt form indicates that it is likely to be more soluble in water compared to its free base form, enhancing its utility in pharmaceutical applications. The compound may exhibit various pharmacological effects, making it of interest in medicinal chemistry. Its stereochemistry, particularly the (2R) configuration, suggests specific interactions with biological targets, which can influence its efficacy and safety profile. Overall, this compound's unique structural features and functional groups position it as a candidate for further research in drug development and therapeutic applications.

Formula: C₁₇H₂₆ClNO₃

InChI: InChI=1/C17H25NO3.ClH/c1-17(2,3)18-10-12(19)11-21-16-9-5-6-13-14(16)7-4-8-15(13)20;/h5-6,9,12,18-19H,4,7-8,10-11H2,1-3H3;1H/t12-;/m1./s1

SMILES: CC(C)(C)NC[C@H](COc1cccc2c1CCCC2=O)O.Cl

(R)-Bunolol HCl

CAS: 27867-05-6

Formula: C₁₇H₂₅NO₃·HCl

Molecular weight: 391.39 36.46

Ref: 4Z-L-187003

ent-Levobunolol Hydrochloride (R-Bunolol Hydrochloride)

Controlled Product

CAS: 27867-05-6

Applications A non-selective ß-adrenoceptor antagonist used as an anticonvulsant. The enantiomer of Levobunolol (L335000).
References Kaplan, H.R., et al.: Eur. J. Pharm., 16, 237 (1971), DiCarlo,F.J., et al.: Clin. Pharm. Ther., 22, 858 (1977)

Formula: C₁₇H₂₅NO₃·ClH

Color and Shape: Neat

Molecular weight: 327.85

Ref: TR-L335010