CAS 27876-94-4

Crocetin

Description:

Crocetin is a carotenoid compound primarily derived from saffron, the dried stigma of Crocus sativus. It is known for its vibrant orange-red color and is classified as a dicarboxylic acid. Crocetin exhibits a variety of biological activities, including antioxidant, anti-inflammatory, and potential neuroprotective effects. Its structure features a long hydrocarbon chain with conjugated double bonds, contributing to its color and reactivity. Crocetin is soluble in organic solvents but has limited solubility in water. It is often studied for its potential therapeutic applications, particularly in the fields of cancer research and neurodegenerative diseases. Additionally, crocetin is recognized for its role in enhancing the bioavailability of other compounds, making it of interest in nutritional and pharmaceutical formulations. Overall, crocetin's unique properties and health benefits make it a significant subject of research in both natural product chemistry and medicinal applications.

Formula: C₂₀H₂₄O₄

InChI: InChI=1S/C20H24O4/c1-15(11-7-13-17(3)19(21)22)9-5-6-10-16(2)12-8-14-18(4)20(23)24/h5-14H,1-4H3,(H,21,22)(H,23,24)/b6-5+,11-7+,12-8+,15-9+,16-10+,17-13+,18-14+

InChI key: InChIKey=PANKHBYNKQNAHN-MQQNZMFNSA-N

SMILES: C(=C(/C(O)=O)\C)\C=C\C(=C\C=C\C=C(\C=C\C=C(\C(O)=O)/C)/C)\C

Synonyms:

• (2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-Tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioic acid
• (2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethylhexadeca-2,4,6,8,10,12,14-heptaenedioic acid
• (2Z,4E,6Z,8E,10E,12E,14Z)-2,6,11,15-tetramethylhexadeca-2,4,6,8,10,12,14-heptaenedioic acid
• 2,4,6,8,10,12,14-Hexadecaheptaenedioic acid, 2,6,11,15-tetramethyl-, (2E,4E,6E,8E,10E,12E,14E)-
• 2,4,6,8,10,12,14-Hexadecaheptaenedioic acid, 2,6,11,15-tetramethyl-, (all-E)-
• 8,8'-Diapo-psi,psi-carotenedioic acid
• 8,8'-Diapocarotenedioic acid
• 8,8′-Diapo-ψ,ψ-carotenedioic acid
• Apocarotenic acid
• Ccris 7484
• Ci 75100
• Crobit P
• Crocetin (stable)
• Leaf 4L 6715
• Leaf-4L6715
• Natural yellow 6
• Nsc 407300
• Stable crocetin
• Transcrocetin
• trans-Crocetin
• α-Crocetin

8,8'-Diapocarotenedioic acid

CAS: 27876-94-4

Formula: C₂₀H₂₄O₄

Purity: %

Color and Shape: Solid

Molecular weight: 328.4022

Ref: IN-DA00BD4L

(2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-Tetramethylhexadeca-2,4,6,8,10,12,14-Heptaenedioic Acid

CAS: 27876-94-4

(2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-Tetramethylhexadeca-2,4,6,8,10,12,14-Heptaenedioic Acid

Purity: 98%

Molecular weight: 328.40g/mol

Ref: 54-OR1007949

Transcrocetin

CAS: 27876-94-4

Transcrocetin

Purity: ≥95%

Molecular weight: 328.4g/mol

Ref: 54-BUP06223

Crocetin

CAS: 27876-94-4

Formula: C₂₀H₂₄O₄

Purity: ≥ 95.0%

Color and Shape: Red to dark red solid

Molecular weight: 328.40

Ref: 7W-GP7582

Crocetin

CAS: 27876-94-4

Formula: C₂₀H₂₄O₄

Purity: 95%~99%

Molecular weight: 328.408

Ref: BP-BP0405

Transcrocetin

CAS: 27876-94-4

Transcrocetin (8,8'-Diapocarotenedioic Acid) is a singlet oxygen quencher.

Formula: C₂₀H₂₄O₄

Purity: 97.63% - 99.2%

Color and Shape: Solid

Molecular weight: 328.40

Ref: TM-T4S0171

Crocetin

CAS: 27876-94-4

Acyclic polybasic carboxylic acid

Formula: C₂₀H₂₄O₄

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 328.4

Ref: 5G-86280

Crocetin

CAS: 27876-94-4

Stability Light Sensitive
Applications Crocetin is a carotenoid derived from saffron, and is shown to have anticancer effects in both human adenocarcinoma gastric cancer cells and rat model of gastric cancer.
References Bathaie, S. Z., et al.: Biochem. Cell Bio., 91, 397 (2013); Nam K. N., et al.: Euro. J. Pharmac., 648(1-3), 110 (2010);

Formula: C₂₀H₂₄O₄

Color and Shape: Neat

Molecular weight: 328.4

Ref: TR-C794950

trans-Crocetin - 70%

CAS: 27876-94-4

trans-Crocetin - 70% is a highly purified carotenoid compound, which is derived from saffron (Crocus sativus) stigmas. Its molecular structure allows it to act as a potent antioxidant, disrupting oxidative stress pathways by scavenging free radicals and inhibiting lipid peroxidation. This mode of action is critical because it can potentially protect cellular components from damage and modulate various biochemical pathways.

Formula: C₂₀H₂₄O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 328.4 g/mol

Ref: 3D-FC63172

trans-Crocetin-98%

CAS: 27876-94-4

trans-Crocetin-98% is a high-purity carotenoid, which is a type of organic pigment. It is derived from the stigmas of the saffron (Crocus sativus) flower, where it is obtained through meticulous extraction processes to ensure its purity and efficacy. trans-Crocetin acts primarily as an antioxidant, neutralizing free radicals and reducing oxidative stress within biological systems. It modulates various signaling pathways, which can result in neuroprotective, anti-inflammatory, and potential anti-cancer activities.

Formula: C₂₀H₂₄O₄

Purity: Min. 95%

Color and Shape: Orange Red Powder

Molecular weight: 328.4 g/mol

Ref: 3D-FC158063