CAS: 278779-30-9 - GW 4064

Formula: C₂₈H₂₂Cl₃NO₄

InChI: InChI=1S/C28H22Cl3NO4/c1-16(2)27-21(26(32-36-27)25-22(29)7-4-8-23(25)30)15-35-20-12-11-18(24(31)14-20)10-9-17-5-3-6-19(13-17)28(33)34/h3-14,16H,15H2,1-2H3,(H,33,34)

InChI key: InChIKey=BYTNEISLBIENSA-UHFFFAOYSA-N

SMILES: O=C(O)C=1C=CC=C(C=CC2=CC=C(OCC=3C(=NOC3C(C)C)C=4C(Cl)=CC=CC4Cl)C=C2Cl)C1

Synonyms:

• 3-(2,6-Dichlorophenyl)-4-(3'-carboxy-2-chlorostilben-4-yl)oxymethyl-5-isopropylisoxazole
• 3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}phenyl)ethenyl]benzoic acid
• 3-[2-[2-Chloro-4-[[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methoxy]phenyl]ethenyl]benzoic acid
• Benzoic acid, 3-[2-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methoxy]phenyl]ethenyl]-

3-[2-[2-Chloro-4-[[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methoxy]phenyl]ethenyl]benzoic acid

CAS: 278779-30-9

• Formula: C₂₈H₂₂Cl₃NO₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 542.8376

GW4064

CAS: 278779-30-9

• Formula: C₂₈H₂₂Cl₃NO₄
• Molecular weight: 542.84

GW 4064

CAS: 278779-30-9

• Formula: C₂₈H₂₂Cl₃NO₄
• Purity: >95.0%(HPLC)(qNMR)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 542.84

GW 4064

CAS: 278779-30-9

GW 4064 is an effective farnesoid X receptor (FXR) agonist (EC50 =65 nM).

• Formula: C₂₈H₂₂Cl₃NO₄
• Purity: 97.47% - 99.94%
• Color and Shape: Solid
• Molecular weight: 542.84

GW 4064

CAS: 278779-30-9

Applications A novel nonsteroidal FXR nuclear receptor agonist. References Makishima, M., et al.: Science, 284, …

• Formula: C₂₈H₂₂Cl₃NO₄
• Color and Shape: Neat
• Molecular weight: 542.84

GW 4064

CAS: 278779-30-9

Farnesoid X receptor agonist

• Formula: C₂₈H₂₂Cl₃NO₄
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 542.84 g/mol