CAS 27912-14-7

Levobunolol hydrochloride

Description:

Levobunolol hydrochloride is a non-selective beta-adrenergic antagonist primarily used in the treatment of elevated intraocular pressure in conditions such as glaucoma and ocular hypertension. It is characterized by its ability to reduce aqueous humor production, thereby lowering intraocular pressure. The substance is a white to off-white crystalline powder that is soluble in water and exhibits a pH range suitable for ophthalmic formulations. Levobunolol hydrochloride has a relatively low molecular weight and is known for its long duration of action, making it effective for once or twice daily dosing. Its mechanism of action involves blocking beta-adrenergic receptors in the eye, which leads to decreased fluid production. Additionally, it may have systemic effects, although these are generally minimized when used topically in eye drops. As with any medication, potential side effects can include ocular irritation, dry eyes, and systemic effects such as bradycardia or hypotension, particularly in sensitive individuals. Overall, Levobunolol hydrochloride is a valuable therapeutic agent in managing specific ocular conditions.

Formula: C₁₇H₂₅NO₃·ClH

InChI: InChI=1S/C17H25NO3.ClH/c1-17(2,3)18-10-12(19)11-21-16-9-5-6-13-14(16)7-4-8-15(13)20;/h5-6,9,12,18-19H,4,7-8,10-11H2,1-3H3;1H/t12-;/m0./s1

InChI key: InChIKey=DNTDOBSIBZKFCP-YDALLXLXSA-N

SMILES: O(C[C@H](CNC(C)(C)C)O)C1=C2C(=CC=C1)C(=O)CCC2.Cl

Synonyms:

• (2S)-N-tert-butyl-2-hydroxy-3-[(5-oxo-5,6,7,8-tetrahydronaphthalen-1-yl)oxy]propan-1-aminium chloride
• (S)-5-(3-(tert-Butylamino)-2-hydroxypropoxy)-3,4-dihydronaphthalen-1(2H)-one hydrochloride
• 1(2H)-Naphthalenone, 5-[(2S)-3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-, hydrochloride
• 1(2H)-Naphthalenone, 5-[(2S)-3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-, hydrochloride (1:1)
• 1(2H)-Naphthalenone, 5-[3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-, hydrochloride, (-)-
• 1(2H)-Naphthalenone, 5-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-, hydrochloride, (S)-
• Ag 901
• Betagan
• Gotensin
• Levobunolol Hydrochloride
• N-tert-butyl-2-hydroxy-3-[(5-oxo-5,6,7,8-tetrahydronaphthalen-1-yl)oxy]propan-1-aminium chloride
• Vitagan
• W 7000A

Levobunolol hydrochloride

CAS: 27912-14-7

Levobunolol hydrochloride

Formula: C₁₇H₂₅NO₃HCl

Purity: 99.9%

Color and Shape: Off White Solid

Molecular weight: 327.16012

Ref: 47-356

Levobunolol Hydrochloride

CAS: 27912-14-7

Aromatic amino-alcohol-phenols, aromatic amino-acid-phe

Formula: C₁₇H₂₅NO₃·ClH

Color and Shape: Powder

Molecular weight: 327.16012

Ref: 45-1359801

Levobunolol hydrochloride

CAS: 27912-14-7

Formula: C₁₇H₂₆ClNO₃

Molecular weight: 327.85

Ref: 7W-GP6911

Levobunolol HCl

CAS: 27912-14-7

Formula: C₁₇H₂₅NO₃·HCl

Molecular weight: 291.39 36.46

Ref: 4Z-L-187001

Levobunolol Hydrochloride

Controlled Product

CAS: 27912-14-7

Stability Light Sensitive
Applications A non-selective ß-adrenoceptor antagonist used as an anticonvulsant.
References Kaplan, H.R., et al.: Eur. J. Pharm., 16, 237 (1971), DiCarlo,F.J., et al.: Clin. Pharm. Ther., 22, 858 (1977)

Formula: C₁₇H₂₅NO₃·ClH

Color and Shape: Neat

Molecular weight: 327.85

Ref: TR-L335000

Levobunolol hydrochloride

CAS: 27912-14-7

Levobunolol hydrochloride 是一种非选择性的 β-肾上腺素受体阻滞剂，可用于治疗青光眼和上斜肌肌障碍的研究。

Formula: C₁₇H₂₆ClNO₃

Purity: 98.49% - >99.99%

Color and Shape: Solid

Molecular weight: 327.85

Ref: TM-T15742