CAS 2792-72-5

5,5,5-Trifluoroleucine

Description:

5,5,5-Trifluoroleucine is a synthetic amino acid characterized by the presence of three fluorine atoms attached to the carbon chain. It is an analog of leucine, one of the essential amino acids, and is notable for its unique properties due to the electronegative fluorine substituents. This compound is typically used in biochemical research, particularly in studies involving protein structure and function, as it can influence the folding and stability of proteins. The presence of fluorine can also affect the hydrophobicity and overall polarity of the molecule, making it a useful tool in the design of peptides and proteins with altered characteristics. 5,5,5-Trifluoroleucine is generally stable under standard laboratory conditions but should be handled with care due to the potential reactivity of fluorinated compounds. Its molecular structure contributes to its distinct physical and chemical properties, which can be leveraged in various applications, including drug design and materials science.

Formula: C₆H₁₀F₃NO₂

InChI: InChI=1S/C6H10F3NO2/c1-3(6(7,8)9)2-4(10)5(11)12/h3-4H,2,10H2,1H3,(H,11,12)

InChI key: InChIKey=XFGVJLGVINCWDP-UHFFFAOYSA-N

SMILES: C(C(C(F)(F)F)C)C(C(O)=O)N

Synonyms:

• 2-Amino-5,5,5-trifluoro-4-methylpentanoic acid
• 5',5',5'-Trifluoroleucine
• 5,5,5-Trifluoro-<span class="text-smallcaps">DL</span>-leucine
• 5,5,5-Trifluoroleucine
• 5,5,5-trifluoro-L-leucine
• <span class="text-smallcaps">DL</span>-5,5,5-Trifluoroleucine
• <span class="text-smallcaps">DL</span>-Leucine, 5,5,5-trifluoro-
• DL-5',5',5'-Trifluoroleucine
• DL-Leucine, 5,5,5-trifluoro-
• Leucine, 5,5,5-trifluoro-
• Leucine, 5,5,5-trifluoro-, <span class="text-smallcaps">DL</span>-
• Leucine, 5,5,5-trifluoro-, DL-
• NSC 90440
• Norvaline, 5,5,5-trifluoro-4-methyl-, <span class="text-smallcaps">DL</span>-
• Norvaline, 5,5,5-trifluoro-4-methyl-, DL-
• Trifluoroleucine

5,5,5-Trifluoro-DL-leucine

CAS: 2792-72-5

Formula: C₆H₁₀F₃NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 185.1443

Ref: IN-DA00BDWE

5,5,5-Trifluoro-DL-leucine

CAS: 2792-72-5

Formula: C₆H₁₀F₃NO₂

Molecular weight: 185.15

Ref: 7W-GM2850

5,5,5-Trifluoro-DL-leucine

CAS: 2792-72-5

5,5,5-Trifluoro-DL-leucine

Formula: C₆H₁₀F₃NO₂

Purity: 97%

Color and Shape: solid

Molecular weight: 185.1443g/mol

Ref: 54-PC7392

5,5,5-Trifluoro-DL-leucine

CAS: 2792-72-5

5,5,5-Trifluoro-DL-leucine is a chemical compound that has been shown to be stable in the presence of hydrogen and can be used as an analog for leucine. It has been shown to bind with the ribosome and inhibit protein synthesis in bacteria. 5,5,5-Trifluoro-DL-leucine binds to the ribosomal A site and blocks peptide bond formation. It also inhibits glucose monitoring by interfering with the binding of glucose to the G protein. 5,5,5-Trifluoro-DL-leucine also has structural properties that are similar to those of 2,3,-dihydrobenzofuran (DHF). This similarity may account for its ability to denature proteins.

Formula: C₆H₁₀F₃NO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 185.14 g/mol

Ref: 3D-FT29687

5,5,5-Trifluoro-DL-leucine

CAS: 2792-72-5

Purity: 98%

Molecular weight: 185.146

Ref: 10-F986991