Cyclopropanecarbonitrile, with the CAS number 2793405-20-4, is a complex organic compound characterized by its unique structural features. It contains a cyclopropane ring, which is a three-membered carbon ring known for its strain and reactivity. The presence of a carbonitrile functional group (-C≡N) indicates that it has a cyano group, contributing to its potential reactivity and applications in organic synthesis. Additionally, the compound features a substituted pyrazino-pyrimido-benzoxazepine structure, which suggests it may exhibit interesting biological activities, possibly as a pharmaceutical agent. The presence of multiple fluorine atoms in its structure indicates that it may possess enhanced lipophilicity and metabolic stability, which are desirable traits in drug design. Overall, this compound's intricate architecture and functional groups make it a subject of interest in medicinal chemistry and material science, although specific properties such as solubility, melting point, and reactivity would require empirical data for comprehensive characterization.

Cyclopropanecarbonitrile, 1-[[(4aS)-12-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-1,2,4,4a,5,6-hexahydro-10-methyl-3H-pyrazino[2,1-d]pyrimido[5,4-h][1,5]benzoxazepin-3-yl]carbonyl]-

2793405-20-4: Cyclopropanecarbonitrile, with the CAS number 2793405-20-4, is a complex organic compound characterized by its unique structural features. It contains a cyclopropane ring, which is a three-membered carbon ring known for its strain and reactivity. The presence of a carbonitrile functional group (-C≡N) indicates that it has a cyano group, contributing to its potential reactivity and applications in organic synthesis. Additionally, the compound features a substituted pyrazino-pyrimido-benzoxazepine structure, which suggests it may exhibit interesting biological activities, possibly as a pharmaceutical agent. The presence of multiple fluorine atoms in its structure indicates that it may possess enhanced lipophilicity and metabolic stability, which are desirable traits in drug design. Overall, this compound's intricate architecture and functional groups make it a subject of interest in medicinal chemistry and material science, although specific properties such as solubility, melting point, and reactivity would require empirical data for comprehensive characterization.

SOS1-IN-14 是选择性的、有效的、口服具有活力的 SOS1 抑制剂 (IC50: 3.9 nM)。SOS1-IN-14 能够利用 P-糖蛋白介导的外排机制在肠道内被吸收。SOS1-IN-14 能够用于 KRAS 突变的癌症的研究，且抑瘤效果比 BI-3406 好。

CAS 2793405-20-4

Cyclopropanecarbonitrile, 1-[[(4aS)-12-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-1,2,4,4a,5,6-hexahydro-10-methyl-3H-pyrazino[2,1-d]pyrimido[5,4-h][1,5]benzoxazepin-3-yl]carbonyl]-

SOS1-IN-14

Ref: TM-T63887