CAS 27955-44-8

4-methyl-6-phenylpyrimidine-2-thiol

Description:

4-Methyl-6-phenylpyrimidine-2-thiol, with the CAS number 27955-44-8, is a heterocyclic organic compound that features a pyrimidine ring substituted with a methyl group and a phenyl group, along with a thiol (-SH) functional group. This compound typically exhibits characteristics common to thiols, such as a strong, often unpleasant odor and the ability to form disulfide bonds. The presence of the thiol group makes it reactive, particularly in nucleophilic substitution reactions. The methyl and phenyl substituents can influence its solubility, stability, and reactivity, often enhancing its lipophilicity. This compound may be used in various applications, including organic synthesis and as a potential building block in pharmaceuticals or agrochemicals. Its unique structure allows for interactions with biological systems, which may be of interest in medicinal chemistry. As with many thiols, it may also exhibit antioxidant properties, contributing to its potential utility in various chemical and biological contexts.

Formula: C₁₁H₁₀N₂S

InChI: InChI=1/C11H10N2S/c1-8-7-10(13-11(14)12-8)9-5-3-2-4-6-9/h2-7H,1H3,(H,12,13,14)

SMILES: Cc1cc(c2ccccc2)nc(n1)S

Synonyms:

• 2-Pyrimidinethiol, 4-methyl-6-phenyl-
• 4-Methyl-6-phenylpyrimidine-2-thiol

4-Methyl-6-phenylpyrimidine-2-thiol

CAS: 27955-44-8

Formula: C₁₁H₁₀N₂S

Color and Shape: Solid

Molecular weight: 202.2755

Ref: IN-DA007LXT

4-Methyl-6-phenyl-pyrimidine-2-thiol

CAS: 27955-44-8

4-Methyl-6-phenyl-pyrimidine-2-thiol is a copper(II) dehalogenating agent that belongs to the group of amplifiers. It has been used in the preparation of syntheses, including as an intermediate in the synthesis of phenylpyrimidines and amidines. The synthesis of 4-methyl-6-phenyl-pyrimidine-2-thiol can be accomplished by condensation of phleomycin with a biaryl. This reaction is followed by oxidation to give a biaryl sulfone, which is then reduced with hydrogen gas and ammonium formate.

Formula: C₁₁H₁₀N₂S

Purity: Min. 95%

Molecular weight: 202.28 g/mol

Ref: 3D-NM57414