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CAS 2800-34-2

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10-Formyltetrahydrofolate

Description:
10-Formyltetrahydrofolate, also known as formyltetrahydrofolate or 10-formyl-THF, is a derivative of tetrahydrofolate, a vital coenzyme in various biological processes. It plays a crucial role in one-carbon metabolism, particularly in the synthesis of nucleotides and amino acids. This compound is characterized by its formyl group attached to the tetrahydrofolate structure, which enhances its reactivity in biochemical pathways. It is involved in the transfer of one-carbon units, making it essential for cellular processes such as DNA synthesis and repair. 10-Formyltetrahydrofolate is typically found in the form of a salt or as a stable derivative in laboratory settings, and it is soluble in water, which facilitates its biological functions. The compound is also significant in the context of folate metabolism and can be synthesized from other folate derivatives. Its CAS number, 2800-34-2, is used for identification in chemical databases and regulatory contexts. Overall, 10-formyltetrahydrofolate is a key player in metabolic pathways, underscoring its importance in biochemistry and nutrition.
Formula:C20H23N7O7
InChI:InChI=1/C20H23N7O7/c21-20-25-16-15(18(32)26-20)23-11(7-22-16)8-27(9-28)12-3-1-10(2-4-12)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,11,13,23H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,22,25,26,32)/t11-,13+/m1/s1
InChI key:InChIKey=AUFGTPPARQZWDO-YUZLPWPTSA-N
SMILES:O=C1C2=C(NCC(CN(C=O)C3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)N2)NC(N)=N1
Synonyms:
  • 10-Formyl-(6RS)-tetrahydrofolic acid
  • 10-Formyl-5,6,7,8-tetrahydrofolic acid
  • 10-Formyltetrahydrofolate
  • 10-Formyltetrahydrofolic acid
  • 10-Formyltetrahydropteroylglutamic acid
  • 10-Fthf
  • 2-[(4-{[(2-Amino-4-oxo-1,4,5,6,7,8-hexahydro-6-pteridinyl)methyl](formyl)amino}benzoyl)amino]pentandis?ure
  • 2-[(4-{[(2-Amino-4-oxo-1,4,5,6,7,8-hexahydro-6-pteridinyl)methyl](formyl)amino}benzoyl)amino]pentanedioic acid
  • <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]formylamino]benzoyl]-
  • <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2-amino-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]formylamino]benzoyl]-
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