CAS 28002-70-2: Framycetin sulfate

Description: Framycetin sulfate, with the CAS number 28002-70-2, is an aminoglycoside antibiotic derived from the bacterium *Friedländer's bacillus*. It is primarily used for its antibacterial properties, particularly against Gram-negative bacteria. The substance is characterized by its ability to inhibit bacterial protein synthesis by binding to the 30S ribosomal subunit, which disrupts the translation process. Framycetin sulfate is often utilized in topical formulations for treating skin infections and is also found in some ophthalmic preparations. It is soluble in water and exhibits a relatively low toxicity profile when applied topically. However, like other aminoglycosides, it can pose risks of ototoxicity and nephrotoxicity when used systemically. The sulfate form enhances its solubility and stability, making it suitable for pharmaceutical applications. As with any antibiotic, the emergence of resistance is a concern, necessitating careful consideration of its use in clinical settings.

Formula: C₂₃H₄₆N₆O₁₃·xH₂O₄S

InChI: InChI=1S/C23H46N6O13.H2O4S/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;1-5(2,3)4/h5-23,30-36H,1-4,24-29H2;(H2,1,2,3,4)/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;/m1./s1

InChI key: InChIKey=OIXVKQDWLFHVGR-WQDIDPJDSA-N

SMILES: O=S(=O)(O)O.OCC1OC(OC2C(O)C(N)CC(N)C2OC3OC(CN)C(O)C(O)C3N)C(O)C1OC4OC(CN)C(O)C(O)C4N

Synonyms:

• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2,6-diamino-2,6-dideoxy-β-<smallcap>L</smallcap>-idopyranosyl-(1→3)-O-β-<smallcap>D</smallcap>-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-<smallcap>D</span>-glucopyranosyl-(1→4)]-2-deoxy-, sulfate (1:?)
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2,6-diamino-2,6-dideoxy-β-<smallcap>L</smallcap>-idopyranosyl-(1→3)-O-β-<smallcap>D</smallcap>-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-<smallcap>D</span>-glucopyranosyl-(1→4)]-2-deoxy-, sulfate (salt)
• D-Streptamine, O-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1-3)-O-beta-D-ribofuranosyl-(1-5)-O-(2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1-4))-2-deoxy-, sulfate (salt)
• Framycetin sulfate
• Framycin sulfate
• Neomycin B, sulfate (salt)
• Unii-Y3720Kz4Tq
• D-Streptamine, O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-, sulfate (salt)
• D-Streptamine, O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-, sulfate (1:?)

Second International standard for neomycin B

CAS: 28002-70-2

Neomycin B

CAS: 28002-70-2

Aminoglycoside antibiotics

• Formula: C₂₃H₄₆N₆O₁₃·xH₂SO₄
• Color and Shape: White Powder
• Molecular weight: 908.88

D-Streptamine, O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-, sulfate (1:?)

CAS: 28002-70-2

• Formula: C₂₃H₄₈N₆O₁₇S
• Color and Shape: Solid
• Molecular weight: 712.7222

Neomycin B Sulfate

CAS: 28002-70-2

Stability Hygroscopic Applications Neomycin B Trisulfate is a trisulfate salt analog of Neomycin B (N389983), …

• Formula: C₂₃H₄₆N₆O₁₃·H₂O₄S
• Color and Shape: Neat
• Molecular weight: 712.72

Framycetin sulphate

CAS: 119-04-0 28002-70-24146-30-9

Please enquire for more information about Framycetin sulphate including the price, delivery time and more …

• Formula: C₂₃H₅₂N₆O₂₅S₃
• Purity: Min. 95%
• Molecular weight: 908.88 g/mol