CAS 2802-11-1

Pregn-4-ene-3,20-dione, 21-(acetyloxy)-6-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (6α,11β,16α)-

Description:

Pregn-4-ene-3,20-dione, 21-(acetyloxy)-6-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (6α,11β,16α)-, commonly known as a synthetic steroid, exhibits several notable characteristics. This compound is a derivative of progesterone, featuring modifications that enhance its biological activity and stability. The presence of a fluorine atom at the 6-position contributes to its potency and alters its pharmacokinetic properties. The acetyloxy group at the 21-position enhances solubility and bioavailability, while the hydroxy groups at the 11 and 16 positions are crucial for receptor binding and activity. The bis(oxy) group at the 16 and 17 positions introduces steric hindrance, which can influence the compound's interaction with biological targets. This steroid is primarily utilized in therapeutic applications, particularly in hormone replacement therapies and as an anti-inflammatory agent. Its structural modifications allow for a tailored pharmacological profile, making it effective in various clinical settings. As with many synthetic steroids, careful consideration of dosage and potential side effects is essential in its application.

Formula: C₂₆H₃₅FO₇

InChI: InChI=1S/C26H35FO7/c1-13(28)32-12-20(31)26-21(33-23(2,3)34-26)10-16-15-9-18(27)17-8-14(29)6-7-24(17,4)22(15)19(30)11-25(16,26)5/h8,15-16,18-19,21-22,30H,6-7,9-12H2,1-5H3/t15-,16-,18-,19-,21+,22+,24-,25-,26+/m0/s1

InChI key: InChIKey=AUDPKCCPWYXNEV-XTLNBZDDSA-N

SMILES: C(COC(C)=O)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(OC(C)(C)O2)[H])([C@]4([C@]([C@@H](O)C3)([C@]5(C)C([C@@H](F)C4)=CC(=O)CC5)[H])[H])[H]

Synonyms:

• 2-[(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS,12S)-12-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-2-oxo-2,3,4,4a,4b,5,6,6a,9a,10,10a,10b,11,12-tetradecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl]-2-oxoethyl acetate
• 2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, pregn-4-ene-3,20-dione deriv.
• 6alpha-Fluoro-11beta,21-dihydroxy-16alpha,17-(isopropylidenedioxy)pregn-4-ene-3,20-dione 21-acetate
• 6α-Fluoro-16α-hydroxyhydrocortisone 16,17-acetonide 21-acetate
• Flurandrenolone acetate
• Pregn-4-ene-3,20-dione, 21-(acetyloxy)-6-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (6α,11β,16α)-
• Pregn-4-ene-3,20-dione, 6α-fluoro-11β,16α,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone, 21-acetate

Fluocinolone Acetonide EP Impurity G

CAS: 2802-11-1

Formula: C₂₆H₃₅FO₇

Molecular weight: 478.56

Ref: ST-EA-CP-F56007

Fluocinolone Acetonide EP Impurity G

CAS: 2802-11-1

Formula: C₂₆H₃₅FO₇

Molecular weight: 478.56

Ref: 4Z-F-118009

Flurandrenolone Acetate

CAS: 2802-11-1

Impurity Fluocinolone Acetonide EP Impurity G
Applications Flurandrenolone Acetate, is the derivative of Flurandrenolide (F598650), which is a Glucocorticoid, used as an antipsoriatic.
References Pearlman, R., et al.: Int. J. Pharm., 18, 53 (1984), Neufeld, E., et al.: J. Chromatogr., 718, 273 (1998),

Formula: C₂₆H₃₅FO₇

Color and Shape: Neat

Molecular weight: 478.55

Ref: TR-F598655

Flurandrenolone acetate

CAS: 2802-11-1

Flurandrenolone acetate is a steroidal anti-inflammatory drug that is used to treat rheumatoid arthritis. It inhibits the production of inflammatory substances in the body, such as prostaglandins and leukotrienes, by inhibiting the enzyme lipoxygenase. Flurandrenolone acetate has been shown to be effective in treating gelsolin-induced inflammation in rats. Flurandrenolone acetate is also used in some therapies to diagnose inflammatory diseases by detecting an increase in white blood cells. This drug is classified as a halogenated steroid and contains carbon atoms with a halogen atom.

Formula: C₂₆H₃₅FO₇

Purity: Min. 95 Area-%

Molecular weight: 478.5 g/mol

Ref: 3D-CAA80211

Flurandrenolone Acetate

CAS: 2802-11-1

Flurandrenolone Acetate, a synthetic glucocorticoid derived from Flurandrenolide, is used to study skin issues like eczema and psoriasis.

Formula: C₂₆H₃₅FO₇

Color and Shape: Solid

Molecular weight: 478.55

Ref: TM-T72279