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CAS 28034-72-2

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Thymidine, 4',5'-didehydro-5'-deoxy-

Description:
Thymidine, 4',5'-didehydro-5'-deoxy- (CAS 28034-72-2) is a nucleoside analog derived from thymidine, which is a building block of DNA. This compound features a modified structure where the 4' and 5' positions of the sugar moiety are altered, resulting in the absence of a hydroxyl group at the 5' position and the presence of a double bond between the 4' and 5' carbon atoms. These modifications can influence its biological activity, particularly in relation to its incorporation into nucleic acids and its potential as an antiviral or anticancer agent. Thymidine analogs are often studied for their ability to inhibit viral replication or to act as substrates for DNA polymerases. The compound is typically characterized by its solubility in polar solvents and its stability under physiological conditions, although specific stability and reactivity can vary based on environmental factors. Its unique structural features make it a subject of interest in medicinal chemistry and molecular biology research.
Formula:C10H12N2O4
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Found 2 products.
  • 4',5'-Didehydro-5'-deoxythymidine
    Targetmol
    + Info

    4',5'-Didehydro-5'-deoxythymidine

    CAS:
    <p>4',5'-Didehydro-5'-deoxythymidine is a Nucleoside Derivative - 5'-Modified nucleoside, Didehydro-nucleoside.</p>
    Formula:C10H12N2O4
    Color and Shape:Solid
    Molecular weight:224.21

    Ref: TM-TNU1148

  • 4’,5’-Didehydro-5’-deoxythymidine
    Biosynth
    + Info

    4’,5’-Didehydro-5’-deoxythymidine

    CAS:
    <p>4'-5' Didehydro-5'-deoxythymidine is a synthetic nucleoside with antiviral activity. It is structurally related to the natural nucleosides thymine and deoxyadenosine. 4,5-Didehydro-5-deoxythymidine has been shown to be an effective inhibitor of DNA synthesis in vitro, and has been shown to have anti-cancer properties in vivo. This compound binds reversibly to the enzyme DNA polymerase α, which prevents it from incorporating dNTPs into DNA. 4,5-Didehydro-5-deoxythymidine also inhibits ribonucleotide reductase and can inhibit host cell protein synthesis. This drug has low toxicity and does not affect healthy cells.</p>
    Purity:Min. 95%

    Ref: 3D-ND163031

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